Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	18751
Country	Canada

Received	2015-04-27 14:37
Peer-Review Started	2015-04-28 11:03
To Make the First Decision	2015-06-18 16:11
Return for Revision	2015-06-24 15:02
Revised	2015-06-26 04:55
Second Decision	2015-07-17 08:25
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-07-27 17:15
Articles in Press	2015-07-27 17:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-08-19 11:51
Publish the Manuscript Online	2015-08-28 18:30

ISSN	1948-5190 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Update on novel endoscopic therapies to treat gastroesophageal reflux disease: A review
Manuscript Source	Invited Manuscript
All Author List	Jessica Hopkins, Noah J Switzer and Shahzeer Karmali
Funding Agency and Grant Number
Corresponding Author	Dr. Shahzeer Karmali, Center for the Advancement of Minimally Invasive Surgery, Royal Alexandria Hospital, 10240 Kingsway, Edmonton, Alberta T5H 3V9, Canada. shahzeer@ualberta.ca
Key Words	Endoscopy; Reflux; Gastroesophageal reflux disease management; EsophyX; Stretta
Core Tip	While surgical intervention with the Laparo-scopic Nissen Fundoplication remains the gold standard for reflux, endoscopic treatments for gastroesophageal reflux disease have become increasingly popular in recent years. This review of endoscopic methods focuses on two procedures: the Esophyx, a procedure involving endoluminal fundoplication of the gastroesophageal junction, and Stretta, a procedure involving radio-frequency ablation of the gastro-esophageal junction. While these techniques have an acceptable safety profile and lead to subjective improvement in reflux, their objective efficacy remains unclear. The review highlights the lack of standardisation of outcome measures and heterogeneity of assessment tools.
Publish Date	2015-08-28 18:30
Citation	Hopkins J, Switzer NJ, Karmali S. Update on novel endoscopic therapies to treat gastroesophageal reflux disease: A review. World J Gastrointest Endosc 2015; 7(11): 1039-1044
URL	http://www.wjgnet.com/1948-5190/full/v7/i11/1039.htm
DOI	http://dx.doi.org/10.4253/wjge.v7.i11.1039

Full Article (PDF)	WJGE-7-1039.pdf
Full Article (Word)	WJGE-7-1039.doc
Manuscript File	18751-Review.docx
Answering Reviewers	18751-Answering reviewers.pdf
Audio Core Tip	18751-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18751-Conflict-of-interest statement.pdf
Copyright License Agreement	18751-Copyright assignment.pdf
Peer-review Report	18751-Peer-review(s).pdf
Scientific Misconduct Check	18751-Scientific misconduct check.pdf
Scientific Editor Work List	18751-Scientific editor work list .pdf