BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
11/9/2015 6:35:00 PM | Browse: 1187 | Download: 1291
Publication Name World Journal of Hepatology
Manuscript ID 18790
Country/Territory Japan
Received
2015-04-28 18:00
Peer-Review Started
2015-05-01 17:31
To Make the First Decision
2015-07-27 16:11
Return for Revision
2015-08-04 08:44
Revised
2015-08-22 22:03
Second Decision
2015-09-28 14:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-10-13 17:21
Articles in Press
2015-10-13 17:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-10-15 09:27
Publish the Manuscript Online
2015-11-09 18:35
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Topic Highlights
Article Title Ribavirin contributes to eradicate hepatitis C virus through polarization of T helper 1/2 cell balance into T helper 1 dominance
Manuscript Source Invited Manuscript
All Author List Katsuhisa Nakatsuka, Masanori Atsukawa, Masumi Shimizu, Hidemi Takahashi and Chiaki Kawamoto
Funding Agency and Grant Number
Corresponding Author Katsuhisa Nakatsuka, MD, PhD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan. kaynet@nms.ac.jp
Key Words Ribavirin; Forkhead box-P3; T helper 1/2 cell balance; T-regulatory lymphocytes; Inducible co-stimulator; Interleukin-10; Hepatitis C virus infection
Core Tip Ribavirin has the potential to regulate the T-helper (Th) 1/2 cell balance into Th1 dominance by modulating the co-stimulatory signaling between antigen-presenting cells and na?ve Th cells as well as the inhibitory activity of T-regulatory cells. These are considered useful in treating hepatitis C virus infection, especially to inhibit hepatocellular carcinoma development.
Publish Date 2015-11-09 18:35
Citation Nakatsuka K, Atsukawa M, Shimizu M, Takahashi H, Kawamoto C. Ribavirin contributes to eradicate hepatitis C virus through polarization of T helper 1/2 cell balance into T helper 1 dominance. World J Hepatol 2015; 7(25): 2590-2596
URL http://www.wjgnet.com/1948-5182/full/v7/i25/2590.htm
DOI http://dx.doi.org/10.4254/wjh.v7.i25.2590
Full Article (PDF) WJH-7-2590.pdf
Full Article (Word) WJH-7-2590.doc
Manuscript File 18790-Review.docx
Answering Reviewers 18790-Answering reviewers.pdf
Audio Core Tip 18790-Audio core tip.amr
Conflict-of-Interest Disclosure Form 18790-Conflict-of-interest statement.pdf
Copyright License Agreement 18790-Copyright assignment.pdf
Peer-review Report 18790-Peer-review(s).pdf
Scientific Misconduct Check 18790-Scientific misconduct check.pdf
Scientific Editor Work List 18790-Scientific editor work list.pdf