Publication Name	World Journal of Hepatology
Manuscript ID	18821
Country	Brazil

Received	2015-04-28 16:40
Peer-Review Started	2015-05-04 14:12
To Make the First Decision	2015-07-06 17:08
Return for Revision	2015-07-09 13:58
Revised
Second Decision	2015-12-04 17:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-12-15 09:05
Articles in Press	2015-12-15 09:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-22 20:16
Publish the Manuscript Online	2015-12-27 14:34

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Extragastric manifestations of Helicobacter pylori infection: Possible role of bacterium in liver and pancreas diseases
Manuscript Source	Invited Manuscript
All Author List	Elizabeth MA Rabelo-Gonçalves, Bruna M Roesler and José MR Zeitune
Funding Agency and Grant Number
Corresponding Author	Elizabeth MA Rabelo-Gonçalves, BSc, MSc, Laboratory of Gastroenterology and Hepatology, Center of Diagnosis of Digestive Diseases, State University of Campinas, Rua Carlos Chagas 420, Campinas, São Paulo 13083-878, Brazil. elizabeth.goncalves@gc.unicamp.br
Key Words	Hepatocellular carcinoma; Cirrhosis; Hepatic encephalopathy; Helicobacter pylori; Nonalcoholic fatty liver disease; Fibrosis; Pancreatitis; Pancreatic cancer; Diabetes mellitus; Metabolic syndrome
Core Tip	Helicobacter pylori (H. pylori) has been associated with several extragastric manifestations, including liver and pancreas diseases. Evidence for its role in the pathogenesis of chronic liver diseases and liver carcinoma is supported by several clinical and experimental studies. Furthermore, epidemiologic and serology-based works have reported a possible association between the microorganism and pancreatic cancer. H. pylori infection has also been linked to the acute and chronic pancreatitis pathogenesis and it could be related to the development of autoimmune pancreatitis, diabetes mellitus and metabolic syndrome. This review summarizes recent findings on the possible role of H. pylori infection in the etiology of liver and pancreas disorders.
Publish Date	2015-12-27 14:34
Citation	Rabelo-Gonçalves EMA, Roesler BM, Zeitune JMR. Extragastric manifestations of Helicobacter pylori infection: Possible role of bacterium in liver and pancreas diseases. World J Hepatol 2015; 7(30): 2968-2979
URL	http://www.wjgnet.com/1948-5182/full/v7/i30/2968.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i30.2968

Full Article (PDF)	WJH-7-2968.pdf
Full Article (Word)	WJH-7-2968.doc
Manuscript File	18821-Review.docx
Answering Reviewers	18821-Answering reviewers.pdf
Audio Core Tip	18821-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	18821-Conflict-of-interest statement.PDF
Copyright License Agreement	18821-Copyright assignment.PDF
Peer-review Report	18821-Peer-review(s).pdf
Scientific Misconduct Check	18821-Scientific misconduct check.pdf
Scientific Editor Work List	18821-Scientific editor work list.pdf