Publication Name	World Journal of Gastroenterology
Manuscript ID	18922
Country	South Korea

Received	2015-04-28 12:16
Peer-Review Started	2015-05-06 15:54
To Make the First Decision	2015-08-31 08:15
Return for Revision	2015-09-01 18:48
Revised	2015-09-30 19:39
Second Decision	2015-11-13 17:31
Accepted by Journal Editor-in-Chief	2015-11-13 18:37
Accepted by Executive Editor-in-Chief	2015-12-01 08:09
Articles in Press	2015-12-01 08:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-04 16:41
Publish the Manuscript Online	2016-01-20 16:55

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Immunology
Manuscript Type	Topic Highlights
Article Title	Natural killer cells in hepatitis C: Current progress
Manuscript Source	Invited Manuscript
All Author List	Joo Chun Yoon, Chang Mo Yang, Youkyong Song and Jae Myun Lee
Funding Agency and Grant Number	Funding Agency Grant Number Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Science ICT & Future Planning 2007-0056092 ICT & Future Planning 2012R1A1A1012207 ICT & Future Planning 2010-0027945
Corresponding Author	Jae Myun Lee, MD, PhD, Department of Microbiology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 120-752, South Korea. jaemyun@yuhs.ac
Key Words	Hepatitis C virus; Natural killer cell; Accessory cell; Virus-host interaction; Immune evasion; Acute hepatitis; Chronic hepatitis; Treatment response
Core Tip	Natural killer (NK) cells protect our body from viral infections by killing infected cells and secreting cytokines that inhibit viral replication. Unlike T lymphocytes that require priming by antigen presenting cells, NK cells directly recognize virus-infected cells and immediately exert antiviral effector functions. Researchers who investigate immunity to hepatitis C virus (HCV), therefore, have been interested in NK cells. This review will give readers an overview of reports on NK cells in hepatitis C and insights into the role of NK cells in the defense against HCV infection, the immunopathogenesis of hepatitis C, and the prediction of the treatment response.
Publish Date	2016-01-20 16:55
Citation	Yoon JC, Yang CM, Song Y, Lee JM. Natural killer cells in hepatitis C: Current progress. World J Gastroenterol 2016; 22(4): 1449-1460
URL	http://www.wjgnet.com/1007-9327/full/v22/i4/1449.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i4.1449

Full Article (PDF)	WJG-22-1449.pdf
Full Article (Word)	WJG-22-1449.doc
Manuscript File	18922-Review.docx
Answering Reviewers	18922-Answering reviewers.pdf
Audio Core Tip	18922-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18922-Conflict-of-interest statement.pdf
Copyright License Agreement	18922-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	18922-Language certificate.pdf
Peer-review Report	18922-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	18922-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	18922-Scientific misconduct check.pdf
Scientific Editor Work List	18922-Scientific editor work list.pdf