Publication Name	World Journal of Gastroenterology
Manuscript ID	18982
Country	Japan

Received	2015-05-01 13:59
Peer-Review Started	2015-05-05 15:58
To Make the First Decision	2015-10-14 17:02
Return for Revision	2015-10-15 14:03
Revised	2015-11-11 16:06
Second Decision	2015-11-26 16:13
Accepted by Journal Editor-in-Chief	2015-11-26 17:05
Accepted by Executive Editor-in-Chief	2015-12-08 16:32
Articles in Press	2015-12-08 16:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-20 14:42
Publish the Manuscript Online	2016-01-31 11:48

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Immunology
Manuscript Type	Topic Highlights
Article Title	Role of regulatory T cell in the pathogenesis of inflammatory bowel disease
Manuscript Source	Invited Manuscript
All Author List	Akiko Yamada, Rieko Arakaki, Masako Saito, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru
Funding Agency and Grant Number	Funding Agency Grant Number Scientific Research from the Ministry of Education, Science, Sport, and Culture of Japan 24659839 Scientific Research from the Ministry of Education, Science, Sport, and Culture of Japan 24689068
Corresponding Author	Naozumi Ishimaru, DDS, PhD, Professor, Department of Oral Molecular Pathology, Tokushima University Graduate School, 3-18-15 Kuramoto, Tokushima 770-8504, Japan. ishimaru.n@tokushima-u.ac.jp
Key Words	Inflammatory bowel disease; Regulatory T cell; Animal model; Therapy
Core Tip	We review the types and functions of regulatory CD4+ T cells (Treg cells) and describe their roles in the pathologies of the inflammatory bowel diseases, i.e., Crohn’s disease and ulcerative colitis. We have paid particular attention to the use of animal models and human studies to elucidate the mechanisms by which Treg cells influence these diseases and have provided an overview of the potential uses of these cells in therapeutic strategies.
Publish Date	2016-01-31 11:48
Citation	Yamada A, Arakaki R, Saito M, Tsunematsu T, Kudo Y, Ishimaru N. Role of regulatory T cell in the pathogenesis of inflammatory bowel disease. World J Gastroenterol 2016; 22(7): 2195-2205
URL	http://www.wjgnet.com/1007-9327/full/v22/i7/2195.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i7.2195

Full Article (PDF)	WJG-22-2195.pdf
Full Article (Word)	WJG-22-2195.doc
Manuscript File	18982-Review.docx
Answering Reviewers	18982-Answering reviewers.pdf
Audio Core Tip	18982-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18982-Conflict-of-interest statement.pdf
Copyright License Agreement	18982-Copyright assignment.pdf
Peer-review Report	18982-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	18982-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	18982-Scientific misconduct check.pdf
Scientific Editor Work List	18982-Scientific editor work list.pdf