Publication Name	World Journal of Gastroenterology
Manuscript ID	18992
Country	Australia

Received	2015-04-30 09:14
Peer-Review Started	2015-05-05 18:12
To Make the First Decision	2015-06-23 14:57
Return for Revision	2015-06-26 16:18
Revised	2015-07-07 16:38
Second Decision	2015-11-03 18:03
Accepted by Journal Editor-in-Chief	2015-11-04 10:01
Accepted by Executive Editor-in-Chief	2015-11-13 17:03
Articles in Press	2015-11-13 17:03
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-11-24 03:44
Typeset the Manuscript	2015-12-14 20:19
Publish the Manuscript Online	2015-12-31 13:27

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Optimal management for alcoholic liver disease: Conventional medications, natural therapy or combination?
Manuscript Source	Invited Manuscript
All Author List	Moon-Sun Kim, Madeleine Ong and Xianqin Qu
Funding Agency and Grant Number
Corresponding Author	Xianqin Qu, PhD, MD, School of Medical and Molecular Biosciences, University of Technology Sydney, PO Box 123, Broadway, Sydney, NSW 2007, Australia. xianqin.qu@uts.edu.au
Key Words	Alcoholic liver disease; Alcohol hepatitis; Conventional medicines; Natural medicines; Hepatic lipid metabolism; Hepatic inflammation; Combination therapy
Core Tip	The aim of this article is to review the impairment of hepatocellular dysfunction in alcoholic liver diseases and their prospective managements. Specifically, we focused on the natural therapies with their efficacies and safeties. Moreover, we summarized molecular mechanisms of herbal therapy to treat alcoholic liver disease (ALD). With evidence-based natural therapy, this article highlighted that the combination of pharmaceutical drugs with naturally occurring agents may offer an optimal management for this complex liver disease. It is worthwhile to conduct large-scale, multiple centre clinical trials further to prove the safety and benefits for the integrative therapy on ALD.
Publish Date	2015-12-31 13:27
Citation	Kim MS, Ong M, Qu X. Optimal management for alcoholic liver disease: Conventional medications, natural therapy or combination? World J Gastroenterol 2016; 22(1): 8-23
URL	http://www.wjgnet.com/1007-9327/full/v22/i1/8.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i1.8

Full Article (PDF)	WJG-22-8.pdf
Full Article (Word)	WJG-22-8.doc
Manuscript File	18992-Review.docx
Answering Reviewers	18992-Answering reviewers.pdf
Audio Core Tip	18992-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18992-Conflict-of-interest statement.pdf
Copyright License Agreement	18992-Copyright assignment.pdf
Peer-review Report	18992-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	18992-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	18992-Scientific misconduct check.pdf
Scientific Editor Work List	18992-Scientific editor work list.pdf