Publication Name	World Journal of Gastroenterology
Manuscript ID	19048
Country	Israel

Received	2015-04-29 21:45
Peer-Review Started	2015-05-07 09:11
To Make the First Decision	2015-06-23 14:58
Return for Revision	2015-06-26 16:53
Revised	2015-07-23 16:41
Second Decision	2015-09-13 22:15
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-09-15 13:33
Articles in Press	2015-09-15 13:33
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-09-26 07:10
Typeset the Manuscript	2015-10-09 14:51
Publish the Manuscript Online	2015-11-03 17:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Non-invasive diagnosis of liver fibrosis and cirrhosis
Manuscript Source	Invited Manuscript
All Author List	Yoav Lurie, Muriel Webb, Ruth Cytter-Kuint, Shimon Shteingart and Gerardo Z Lederkremer
Funding Agency and Grant Number
Corresponding Author	Dr. Yoav Lurie, MD, Liver Unit, Shaare Zedek Medical Center, affiliated with the Hebrew University School of Medicine, Jerusalem 91031, Israel. yoav@szmc.org.il
Key Words	Liver; Fibrosis; Cirrhosis; Non-invasive; Serum biomarkers; Ultrasonography; Computerized tomography; Magnetic resonance imaging
Core Tip	Liver fibrosis (leading to liver cirrhosis), and not inflammation and cytolysis, is the main cause of liver disease-associated morbidity and mortality. During the last 20 years, it has become evident, even to its proponents that liver biopsy, is no longer the “gold-standard”. At most, it is the old standard. Non-invasive diagnostic scores, formulae, and imaging modalities, all of which can be repeated as often as required, are cheaper, better tolerated, safer, and more acceptable to the patient than liver biopsy. Although their accuracy is still controversial, early evidence indicates that they might be at least as good as liver biopsy.
Publish Date	2015-11-03 17:31
Citation	Lurie Y, Webb M, Cytter-Kuint R, Shteingart S, Lederkremer GZ. Non-invasive diagnosis of liver fibrosis and cirrhosis. World J Gastroenterol 2015; 21(41): 11567-11583
URL	http://www.wjgnet.com/1007-9327/full/v21/i41/11567.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i41.11567

Full Article (PDF)	WJG-21-11567.pdf
Full Article (Word)	WJG-21-11567.doc
Manuscript File	19048-Review.docx
Answering Reviewers	19048-Answering reviewers.pdf
Audio Core Tip	19048-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19048-Conflict-of-interest statement.pdf
Copyright License Agreement	19048-Copyright assignment.pdf
Peer-review Report	19048-Peer-review(s).pdf
Scientific Misconduct Check	19048-Scientific misconduct check.pdf
Scientific Editor Work List	19048-Scientific editor work list.pdf