Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	19083
Country	Germany

Received	2015-04-29 13:17
Peer-Review Started	2015-05-07 10:33
To Make the First Decision	2015-06-25 17:44
Return for Revision	2015-06-26 19:45
Revised	2015-07-23 14:47
Second Decision	2015-09-28 16:09
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-10-09 10:59
Articles in Press	2015-10-09 10:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-27 21:27
Publish the Manuscript Online	2015-11-17 08:51

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Biochemistry & Molecular Biology
Manuscript Type	Topic Highlights
Article Title	Individualized treatment of gastric cancer: Impact of molecular biology and pathohistological features
Manuscript Source	Invited Manuscript
All Author List	Yves Dittmar and Utz Settmacher
Funding Agency and Grant Number
Corresponding Author	Yves Dittmar, MD, Department of General, Visceral and Vascular Surgery, University Hospital Jena, Erlanger Allee 101, 07745 Jena, Germany. yves.dittmar@med.uni-jena.de
Key Words	Gastric cancer; Molecular biology; Targeted therapy; Personalized medicine; Signaling pathway
Core Tip	Advanced gastric cancer remains a frequent malignancy with poor prognosis despite multimodal treatment options. Surgery alone has been demonstrated not to be the optimal strategy and is predominantly limited to cases without distant metastases. About one half of gastric cancer patients cannot be cured. Due to its individual heterogeneity on the molecular level these tumors frequently do not respond to systemic treatment. The implementation of the growing knowledge about the molecular behavior of gastric cancer in the development or improvement of target-specific treatment strategies might be one of the major challenges for the next decades.
Publish Date	2015-11-17 08:51
Citation	Dittmar Y, Settmacher U. Individualized treatment of gastric cancer: Impact of molecular biology and pathohistological features. World J Gastrointest Oncol 2015; 7(11): 292-302
URL	http://www.wjgnet.com/1948-5204/full/v7/i11/292.htm
DOI	http://dx.doi.org/10.4251/wjgo.v7.i11.292

Full Article (PDF)	WJGO-7-292.pdf
Full Article (Word)	WJGO-7-292.doc
Manuscript File	19083-Review.doc
Answering Reviewers	19083-Answering reviewers.pdf
Audio Core Tip	19083-Audio core tip.wav
Peer-review Report	19083-Peer-review(s).pdf
Scientific Misconduct Check	19083-Scientific misconduct check.pdf
Scientific Editor Work List	19083-Scientific editor work list.pdf