Publication Name	World Journal of Gastroenterology
Manuscript ID	19084
Country	India

Received	2015-04-29 13:15
Peer-Review Started	2015-05-11 08:17
To Make the First Decision	2015-06-25 20:25
Return for Revision	2015-07-05 15:22
Revised	2015-08-29 16:59
Second Decision	2015-11-19 13:02
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-12-01 08:19
Articles in Press	2015-12-01 08:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-21 15:17
Publish the Manuscript Online	2016-01-06 16:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Insight to drug delivery aspects for colorectal cancer
Manuscript Source	Invited Manuscript
All Author List	Arvind Gulbake, Aviral Jain, Ashish Jain, Ankit Jain and Sanjay K Jain
Funding Agency and Grant Number
Corresponding Author	Sanjay K Jain, Professor, Pharmaceutics Research Projects Laboratory, Department of Pharmaceutical Sciences, Dr. Hari Singh Gour Central University, Sagar 470003, Madhya Pradesh, India. drskjainin@yahoo.com
Key Words	Colorectal cancer; Receptor based targeted therapy; Gene delivery
Core Tip	Colorectal cancer (CRC) is one the major worldwide health problems owing to its high prevalence and mortality rates. It is reported that over 40000 of the adult United Kingdom population are diagnosed with CRC each year. In case of early diagnosis CRC is also one of the most curable types of cancer (cure rates > 90%). This article gives an overview study of causes and etiology of colon cancer, distinct stages from stage from 0 to Ⅳ, some novel therapies are also briefly discussed in article such as receptor (epidermal growth factor receptor, folate receptor, wheat germ agglutinin, VEGF receptor, hyaluronic acid receptor) based targeting therapy; colon targeted proapoptotic anticancer drug delivery system, gene therapy. Recent developments in screening, prevention, biomarker and genomic analysis, nutritional supplement therapy, vaccination, and chemotherapy have improved detection and significant reduction in mortality statistics.
Publish Date	2016-01-06 16:13
Citation	Gulbake A, Jain A, Jain A, Jain A, Jain SK. Insight to drug delivery aspects for colorectal cancer. World J Gastroenterol 2016; 22(2): 582-599
URL	http://www.wjgnet.com/1007-9327/full/v22/i2/582.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i2.582

Full Article (PDF)	WJG-22-582.pdf
Full Article (Word)	WJG-22-582.doc
Manuscript File	19084-Review.doc
Answering Reviewers	19084-Answering reviewers.pdf
Audio Core Tip	19084-Audio core tip.mp3
Copyright License Agreement	19084-Copyright assignment.pdf
Peer-review Report	19084-Peer-review(s).pdf
Scientific Misconduct Check	19084-Scientific misconduct check.pdf
Scientific Editor Work List	19084-Scientific editor work list.pdf