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Articles Published Processes
12/6/2015 1:18:00 PM | Browse: 957 | Download: 1900
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Received |
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2015-04-29 13:03 |
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Peer-Review Started |
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2015-05-12 10:47 |
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To Make the First Decision |
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2015-07-19 15:32 |
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Return for Revision |
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2015-07-27 11:21 |
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Revised |
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2015-08-07 04:12 |
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Second Decision |
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2015-09-23 19:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-09-30 08:36 |
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Articles in Press |
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2015-09-30 08:36 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-11-18 09:47 |
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Publish the Manuscript Online |
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2015-12-06 13:18 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Meta-Analysis |
Article Title |
Hybrid therapy for Helicobacter pylori infection: A systemic review and meta-analysis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Ping-I Hsu, Pei-Chin Lin and David Y Graham |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Research Foundation of the Kaohsiung Veterans General Hospital |
VGHKS103-58 |
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Corresponding Author |
David Y Graham, Professor, Department of Medicine/Gastroenterology, Michael E. DeBakey Veterans Affairs Medical Center, and Baylor College of Medicine, Room 3A-320, 2002 Holcombe Blvd., Houston, Tx 77030,
United States. dgraham@bcm.tmc.edu |
Key Words |
Helicobacter pylori; Concomitant therapy; Hybrid therapy; Sequential therapy; Triple therapy |
Core Tip |
This article is aimed to review current evidences of hybrid therapy for Helicobacter pylori infection. The mean cure rates of hybrid therapy by intention-to-treat and per-protocol analyses were 88.5% and 93.3%, respectively. Meta-analysis showed that hybrid therapy was more effective than sequential therapy in the non-Italian population. In contrast, it was less effective than sequential therapy in the Italian population. There was no significant difference in eradication rate between hybrid therapy and concomitant therapy. Reverse hybrid therapy is a new one-step tow-phase treatment, achieving a higher eradication rate than standard triple therapy with similar tolerability and less pharmaceutical cost. |
Publish Date |
2015-12-06 13:18 |
Citation |
Hsu PI, Lin PC, Graham DY. Hybrid therapy for Helicobacter pylori infection: A systemic review and meta-analysis. World J Gastroenterol 2015; 21(45): 12954-12962 |
URL |
http://www.wjgnet.com/1007-9327/full/v21/i45/12954.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v21.i45.12954 |
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