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12/6/2015 1:18:00 PM | Browse: 860 | Download: 1387
Publication Name World Journal of Gastroenterology
Manuscript ID 19098
Country United States
Received
2015-04-29 13:03
Peer-Review Started
2015-05-12 10:47
To Make the First Decision
2015-07-19 15:32
Return for Revision
2015-07-27 11:21
Revised
2015-08-07 04:12
Second Decision
2015-09-23 19:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-09-30 08:36
Articles in Press
2015-09-30 08:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-11-18 09:47
Publish the Manuscript Online
2015-12-06 13:18
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Hybrid therapy for Helicobacter pylori infection: A systemic review and meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Ping-I Hsu, Pei-Chin Lin and David Y Graham
Funding Agency and Grant Number
Funding Agency Grant Number
Research Foundation of the Kaohsiung Veterans General Hospital VGHKS103-58
Corresponding Author David Y Graham, Professor, Department of Medicine/Gastroenterology, Michael E. DeBakey Veterans Affairs Medical Center, and Baylor College of Medicine, Room 3A-320, 2002 Holcombe Blvd., Houston, Tx 77030, United States. dgraham@bcm.tmc.edu
Key Words Helicobacter pylori; Concomitant therapy; Hybrid therapy; Sequential therapy; Triple therapy
Core Tip This article is aimed to review current evidences of hybrid therapy for Helicobacter pylori infection. The mean cure rates of hybrid therapy by intention-to-treat and per-protocol analyses were 88.5% and 93.3%, respectively. Meta-analysis showed that hybrid therapy was more effective than sequential therapy in the non-Italian population. In contrast, it was less effective than sequential therapy in the Italian population. There was no significant difference in eradication rate between hybrid therapy and concomitant therapy. Reverse hybrid therapy is a new one-step tow-phase treatment, achieving a higher eradication rate than standard triple therapy with similar tolerability and less pharmaceutical cost.
Publish Date 2015-12-06 13:18
Citation Hsu PI, Lin PC, Graham DY. Hybrid therapy for Helicobacter pylori infection: A systemic review and meta-analysis. World J Gastroenterol 2015; 21(45): 12954-12962
URL http://www.wjgnet.com/1007-9327/full/v21/i45/12954.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i45.12954
Full Article (PDF) WJG-21-12954.pdf
Full Article (Word) WJG-21-12954.doc
Manuscript File 19098-Review.doc
Answering Reviewers 19098-Answering reviewers.pdf
Audio Core Tip 19098-Audio core tip.mp3
Biostatistics Review Certificate Biostatistics_Statement_20150429030130.doc
Conflict-of-Interest Disclosure Form 19098-Conflict-of-interest statement.pdf
Copyright License Agreement 19098-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 19098-Language certificate.pdf
Supplementary Material Supplementary_Material_20150429022059.pdf
Peer-review Report 19098-Peer-review(s).pdf
Scientific Misconduct Check 19098-Scientific misconduct check.pdf
Scientific Editor Work List 19098-Scientific editor work list.pdf