Publication Name	World Journal of Gastroenterology
Manuscript ID	19107
Country	United States

Received	2015-04-29 11:07
Peer-Review Started	2015-05-12 13:59
To Make the First Decision	2015-09-09 17:32
Return for Revision	2015-09-14 17:07
Revised	2015-09-28 23:49
Second Decision	2015-11-11 16:55
Accepted by Journal Editor-in-Chief	2015-11-11 21:55
Accepted by Executive Editor-in-Chief	2015-11-24 16:48
Articles in Press	2015-11-24 16:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-28 10:42
Publish the Manuscript Online	2016-01-15 14:54

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Protective links between vitamin D, inflammatory bowel disease and colon cancer
Manuscript Source	Invited Manuscript
All Author List	Stacey Meeker, Audrey Seamons, Lillian Maggio-Price and Jisun Paik
Funding Agency and Grant Number	Funding Agency Grant Number AICR 09A136-Rev NIH R21 CA149995-01A1 NIH 5T32DK007742-17
Corresponding Author	Jisun Paik, PhD, Department of Comparative Medicine, University of Washington, Box 357340, 1959 NE Pacific Street, Seattle, WA 98195, United States. jpaik@uw.edu
Key Words	Vitamin D; Inflammatory bowel disease; Colitis; Colon cancer; Inflammation-associated colon cancer; Mouse models
Core Tip	Vitamin D is inversely related to inflammation-associated diseases such as inflammatory bowel disease (IBD) and colon cancer. As vitamin D deficiency and insufficiency are prevalent worldwide, it can significantly impact risk and progression of these diseases. Here we provide an overview of human epidemiologic and animal studies linking vitamin D, IBD and colon cancer. We also review potential mechanisms of vitamin D action that were elucidated by using animal models. Finally, we address current knowledge gaps in this field of research to help determine the potential benefits and risks of using vitamin D to prevent and/or treat IBD and cancer.
Publish Date	2016-01-15 14:54
Citation	Meeker S, Seamons A, Maggio-Price L, Paik J. Protective links between vitamin D, inflammatory bowel disease and colon cancer. World J Gastroenterol 2016; 22(3): 933-948
URL	http://www.wjgnet.com/1007-9327/full/v22/i3/933.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i3.933

Full Article (PDF)	WJG-22-933.pdf
Full Article (Word)	WJG-22-933.doc
Manuscript File	19107-Review.docx
Answering Reviewers	19107-Answering reviewers.pdf
Audio Core Tip	19107-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19107-Conflict-of-interest statement.pdf
Copyright License Agreement	19107-Copyright assignment.pdf
Peer-review Report	19107-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19107-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19107-Scientific misconduct check.pdf
Scientific Editor Work List	19107-Scientific editor work list.pdf