Publication Name	World Journal of Clinical Oncology
Manuscript ID	19108
Country	United States

Received	2015-04-29 11:06
Peer-Review Started	2015-04-29 23:50
To Make the First Decision	2015-06-03 14:41
Return for Revision	2015-06-04 17:58
Revised	2015-07-02 07:04
Second Decision	2015-07-17 08:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-07-27 17:18
Articles in Press	2015-07-27 17:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-09-26 20:47
Publish the Manuscript Online	2015-10-13 10:26

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Research & Experimental Medicine
Manuscript Type	Editorial
Article Title	New insights into tumor dormancy: Targeting DNA repair pathways
Manuscript Source	Invited Manuscript
All Author List	Elizabeth B Evans and Shiaw-Yih Lin
Funding Agency and Grant Number	Funding Agency Grant Number DOD Innovator and Scholar Concept Award W81XWH-12-1-0372
Corresponding Author	Shiaw-Yih Lin, PhD, Deputy Chair, Department of Systems Biology, the University of Texas MD Anderson Cancer Center, 2.SCR3.2020, 7435 Fannin St., Houston, TX 77030, United States. sylin@mdanderson.org
Key Words	Quiescence; Homologous recombination; Non-homologous end joining; Tumor dormancy; DNA repair
Core Tip	One of the main causes of metastasis is tumor dormancy in which cancer cells remain concealed, asymptomatic, and untraceable over a prolonged period of time. Recent studies have suggested that DNA repair mechanisms may contribute to the survival of dormant cancer cells. Under certain conditions, dormant cells can re-enter into the cell cycle and resume proliferation leading to recurrence. Understanding the molecular and cellular regulators underlying the transition from tumor dormancy to metastatic disease may provide insight into how recurrence occurs and also discover strategies that may enhance therapeutic approaches to prevent metastatic cancer.
Publish Date	2015-10-13 10:26
Citation	Evans EB, Lin SY. New insights into tumor dormancy: Targeting DNA repair pathways. World J Clin Oncol 2015; 6(5): 80-88
URL	http://www.wjgnet.com/2218-4333/full/v6/i5/80.htm
DOI	http://dx.doi.org/10.5306/wjco.v6.i5.80

Full Article (PDF)	WJCO-6-80.pdf
Full Article (Word)	WJCO-6-80.doc
Manuscript File	19108-Review.docx
Answering Reviewers	19108-Answering reviewers.pdf
Audio Core Tip	19108-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19108-Conflict-of-interest statement.pdf
Copyright License Agreement	19108-Copyright assignment.pdf
Peer-review Report	19108-Peer-review(s).pdf
Scientific Misconduct Check	19108-Scientific misconduct check.pdf
Scientific Editor Work List	19108-Scientific editor work list.pdf