Publication Name	World Journal of Gastroenterology
Manuscript ID	19110
Country	Spain

Received	2015-04-29 10:58
Peer-Review Started	2015-05-12 14:12
To Make the First Decision	2015-06-02 16:01
Return for Revision	2015-06-09 12:31
Revised	2015-06-23 05:32
Second Decision	2015-08-19 15:11
Accepted by Journal Editor-in-Chief	2015-08-19 16:47
Accepted by Company Editor-in-Chief	2015-08-31 17:53
Articles in Press	2015-08-31 17:53
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-09-09 07:48
Typeset the Manuscript	2015-09-30 11:43
Publish the Manuscript Online	2015-10-23 15:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Immunogenicity and mechanisms impairing the response to vaccines in inflammatory bowel disease
Manuscript Source	Invited Manuscript
All Author List	Alicia C Marín, Javier P Gisbert and María Chaparro
Funding Agency and Grant Number
Corresponding Author	María Chaparro, MD, PhD, Gastroenterology Unit, Hospital Universitario de La Princesa and Instituto de Investigación Sanitaria Princesa, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Americio 17 portal E 2 ºC, 28021 Madrid, Spain. mariachs2005@gmail.com
Key Words	Crohn’s disease; Inflammatory bowel disease; Tumor necrosis factor; Ulcerative colitis; Vaccine; Vaccination; Immunogenicity
Core Tip	Inflammatory bowel disease (IBD) patients are vulnerable to infections owing to the underlying immunological disorder and to the immunosuppressive therapy used to treat the disease. Although some of these infections could be vaccine-preventable, IBD patients show impaired immunogenicity to some vaccines (such as hepatitis B or pneumococcal vaccines). In this review, the authors discuss available data on the immunogenicity of vaccines in IBD patients and summarize current knowledge on the mechanisms that could impair responses to vaccines.
Publish Date	2015-10-23 15:45
Citation	Marín AC, Gisbert JP, Chaparro M. Immunogenicity and mechanisms impairing the response to vaccines in inflammatory bowel disease. World J Gastroenterol 2015; 21(40): 11273-11281
URL	http://www.wjgnet.com/1007-9327/full/v21/i40/11273.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i40.11273

Full Article (PDF)	WJG-21-11273.pdf
Full Article (Word)	WJG-21-11273.doc
Manuscript File	19110-Review.docx
Answering Reviewers	19110-Answering reviewers.pdf
Audio Core Tip	19110-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19110-Conflict-of-interest statement.pdf
Copyright License Agreement	19110-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	19110-Language certificate.pdf
Peer-review Report	19110-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19110-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19110-Scientific misconduct check.pdf
Scientific Editor Work List	19110-Scientific editor work list.pdf