Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	19135
Country	United States

Received	2015-04-29 08:53
Peer-Review Started	2015-05-07 20:07
To Make the First Decision	2015-08-31 16:47
Return for Revision	2015-09-08 10:15
Revised	2015-10-09 00:11
Second Decision	2015-11-17 15:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-12-02 14:11
Articles in Press	2015-12-02 14:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-09 17:43
Publish the Manuscript Online	2016-01-14 20:17

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	MicroRNA in pancreatic ductal adenocarcinoma and its precursor lesions
Manuscript Source	Invited Manuscript
All Author List	Yasmin G Hernandez and Aimee L Lucas
Funding Agency and Grant Number
Corresponding Author	Aimee L Lucas, MD, MS, Assistant Professor of Medicine, Henry Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, Box #1069, New York, NY 10029, United States. aimee.lucas@mssm.edu
Key Words	Pancreatic cancer; MicroRNA; Biomarkers; Pancreatic intraepithelial lesions; Intraductal papillary mucinous neoplasm
Core Tip	Reliable biomarkers are needed to detect pancreatic ductal adenocarcinoma (PDAC) early in order to decrease mortality. In this review, we discuss what the current knowledge is on microRNA (miRNA) in PDAC and its precursor lesions. MiR-21, miR-155, miR-196, miR-210 are dysregulated in tissue, serum, cyst fluid, and stool of PDAC patients. MiR-21, miR-155, and miR-196 are dysregulated in intraductual papillary mucinous neoplasm and pancreatic intraepithelial lesions demonstrating that these miRNAs may serve as potential biomarkers for early stage lesions and cancer.
Publish Date	2016-01-14 20:17
Citation	Hernandez YG, Lucas AL. MicroRNA in pancreatic ductal adenocarcinoma and its precursor lesions. World J Gastrointest Oncol 2016; 8(1): 18-29
URL	http://www.wjgnet.com/1948-5204/full/v8/i1/18.htm
DOI	http://dx.doi.org/10.4251/wjgo.v8.i1.18

Full Article (PDF)	WJGO-8-18.pdf
Full Article (Word)	WJGO-8-18.doc
Manuscript File	19135-Review.docx
Answering Reviewers	19135-Answering reviewers.pdf
Audio Core Tip	19135-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19135-Conflict-of-interest statement.pdf
Copyright License Agreement	19135-Copyright assignment.pdf
Peer-review Report	19135-Peer-review(s).pdf
Scientific Misconduct Check	19135-Scientific misconduct check.pdf
Scientific Editor Work List	19135-Scientific editor work list.pdf