Publication Name	World Journal of Hepatology
Manuscript ID	19172
Country	Japan

Received	2015-05-04 14:48
Peer-Review Started	2015-05-08 10:03
To Make the First Decision	2015-09-08 10:31
Return for Revision	2015-09-13 14:05
Revised	2015-10-29 19:07
Second Decision	2016-01-25 14:31
Accepted by Journal Editor-in-Chief	2016-01-26 16:05
Accepted by Executive Editor-in-Chief	2016-03-09 12:13
Articles in Press	2016-03-09 12:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-10 09:19
Publish the Manuscript Online	2016-03-24 10:34

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Surgery
Manuscript Type	Topic Highlights
Article Title	Preoperative portal vein embolization for hepatocellular carcinoma: consensus and controversy
Manuscript Source	Invited Manuscript
All Author List	Taku Aoki and Keiichi Kubota
Funding Agency and Grant Number
Corresponding Author	Taku Aoki, MD, PhD, Second Department of Surgery, Dokkyo Medical University, 880 Kitakobayashi Mibu, Tochigi 321-0293, Japan. aoki-2su@dokkyomed.ac.jp
Key Words	Hepatocellular carcinoma; Future liver remnant; Poral vein embolization; Liver functional reserve; The associating liver partition and portal vein ligation for staged hepatectomy
Core Tip	Preoperative portal vein embolization (PVE) has been developed to secure the safety of a major hepatic resection by inducing the hypertrophy of the future liver remnant. PVE has been shown to be useful for patients with hepatocellular carcinoma and chronic liver disease. However, the indications should be carefully judged based on the volumetric analysis and evaluation of the liver functional reserve. Recently, a novel technique called the associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) has been introduced to gain a rapid hypertrophy of the future liver remnant; however, at present, data supporting ALPPS in hepatocellular carcinoma with cirrhosis are still very weak.
Publish Date	2016-03-24 10:34
Citation	Aoki T, Kubota K. Preoperative portal vein embolization for hepatocellular carcinoma: Consensus and controversy. World J Hepatol 2016; 8(9): 439-445
URL	http://www.wjgnet.com/1948-5182/full/v8/i9/439.htm
DOI	http://dx.doi.org/10.4254/wjh.v8.i9.439

Full Article (PDF)	WJH-8-439.pdf
Full Article (Word)	WJH-8-439.doc
Manuscript File	19172-Review.docx
Answering Reviewers	19172-Answering reviewers.pdf
Audio Core Tip	19172-Audio core tip.wma
Conflict-of-Interest Disclosure Form	19172-Conflict-of-interset statement.pdf
Copyright License Agreement	19172-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	19172-Language certificate.pdf
Peer-review Report	19172-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19172-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19172-Scientific misconduct check.pdf
Scientific Editor Work List	19172-Scientific editor work list.pdf