Publication Name	World Journal of Gastroenterology
Manuscript ID	19273
Country	Switzerland

Received	2015-05-03 11:47
Peer-Review Started	2015-05-08 20:59
To Make the First Decision	2015-06-02 13:42
Return for Revision	2015-06-06 18:26
Revised	2015-06-19 04:59
Second Decision	2015-09-13 22:15
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-09-15 13:34
Articles in Press	2015-09-15 13:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-30 16:43
Publish the Manuscript Online	2015-11-18 12:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Randomized Clinical Trial
Article Title	Epidural anesthesia improves pancreatic perfusion and decreases the severity of acute pancreatitis
Manuscript Source	Unsolicited Manuscript
All Author List	Samira M Sadowski, Axel Andres, Philippe Morel, Eduardo Schiffer, Jean-Louis Frossard, Alexandra Platon, Pierre-Alexandre Poletti and Leo Bühler
Funding Agency and Grant Number	Funding Agency Grant Number University Hospitals of Geneva to Bühler L
Corresponding Author	Leo Bühler, Professor, Department of Visceral and Transplantation Surgery, University Hospitals of Geneva, Rue Gabrielle Perret-Gentil 4, 1211 Geneva 14. Switzerland. leo.buhler@hcuge.ch
Key Words	Severe acute pancreatitis; Epidural anes­thesia; Pancreatic necrosectomy; Pancreatic perfusion; Computed tomography
Core Tip	We conducted this prospective randomized study to explore the safety of epidural anesthesia (EA), its effect on pancreatic perfusion and the outcome of patients with acute pancreatitis, as high mortality is linked with necrosis of the gland. We found an improvement in perfusion of the pancreas in the EA group. Necrosectomy was performed in 1/13 patients in the EA group vs 4/22 patients in the control group.
Publish Date	2015-11-18 12:39
Citation	Sadowski SM, Andres A, Morel P, Schiffer E, Frossard JL, Platon A, Poletti PA, Bühler L. Epidural anesthesia improves pancreatic perfusion and decreases the severity of acute pancreatitis. World J Gastroenterol 2015; 21(43): 12448-12456
URL	http://www.wjgnet.com/1007-9327/full/v21/i43/12448.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i43.12448

Full Article (PDF)	WJG-21-12448.pdf
Full Article (Word)	WJG-21-12448.doc
Manuscript File	19273-Review.doc
Answering Reviewers	19273-Answering reviewers.pdf
Audio Core Tip	19273-Audio core tip.wav
Biostatistics Review Certificate	19273-Biostatistics statement.pdf
Clinical Trial Registration Statement	19273-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form	19273-Conflict-of-interest statement.pdf
Copyright License Agreement	19273-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20150502042222.pdf
Institutional Review Board Approval Form or Document	19273-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	19273-Language certificate.pdf
Peer-review Report	19273-Peer-review(s).pdf
Scientific Misconduct Check	19273-Scientific misconduct check.pdf
Scientific Editor Work List	19273-Scientific editor work list.pdf