Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	19276
Country	Oman

Received	2015-05-03 11:38
Peer-Review Started	2015-05-08 20:49
To Make the First Decision	2015-07-27 16:08
Return for Revision	2015-08-04 11:49
Revised	2015-08-24 22:50
Second Decision	2015-12-07 09:09
Accepted by Journal Editor-in-Chief	2015-12-08 04:47
Accepted by Executive Editor-in-Chief	2016-02-24 14:18
Articles in Press	2016-02-24 14:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-04-08 15:43
Publish the Manuscript Online	2016-04-20 11:37

ISSN	1948-9366 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Surgery
Manuscript Type	Systematic Reviews
Article Title	Duodenal injury post laparoscopic cholecystectomy: Incidence, mechanism, management and outcome
Manuscript Source	Invited Manuscript
All Author List	Norman Oneil Machado
Funding Agency and Grant Number
Corresponding Author	Dr. Norman Oneil Machado, Department of Surgery, Sultan Qaboos University Hospital, PO Box 38, Street 5, Road A, House 19, SQU campus, Muscat 123, Oman. oneilnorman@gmail.com
Key Words	Laparoscopic cholecystectomy; Duodenal injury; Duodenorapphy
Core Tip	Inadvertent duodenal injury is a rare potentially fatal complication of laparoscopic cholecystectomy. Such injuries often go unrecognized at the time of the procedure and manifest later with significant morbidity and mortality. Literature review revealed 74 cases of duodenal injury. The injury was caused by cautery in 46%, dissection in 39% and retraction in 14% of the cases. The predominant site of injury was to the 2nd part in 61% and in 31% to 1st part. Duodenorapphy was the primary treatment carried out in 63% of the cases among which 21% was laparoscopically. When detected on table, 88.9% survived in contrast to 76.5% detected later. Overall mortality was 18%. The major impact of this review in clinical practice is in emphasizing the need for prompt detection of a potential duodenal injury in every patient who has unexplained postoperative course following a difficult laparoscopic cholecystectomy due to gall bladder adhesions or dissection. The change of clinical practice it should lead to is an attempt by surgeons in early detection of potential duodenal injury in such patients, which could be achieved by estimating the amylase content in subhepatic fluid collection or by upper gastrointestinal contrast studies. It also highlights the need for immediate surgical repair as any delay beyond the first postoperative day has adverse effect on outcome.
Publish Date	2016-04-20 11:37
Citation	Machado NO. Duodenal injury post laparoscopic cholecystectomy: Incidence, mechanism, management and outcome. World J Gastrointest Surg 2016; 8(4): 335-344
URL	http://www.wjgnet.com/1948-9366/full/v8/i4/335.htm
DOI	http://dx.doi.org/10.4240/wjgs.v8.i4.335

Full Article (PDF)	WJGS-8-335.pdf
Full Article (Word)	WJGS-8-335.doc
Manuscript File	19276-Review.docx
Answering Reviewers	19276-Answering reviewers.pdf
Audio Core Tip	19276-Audio core tip.aac
Biostatistics Review Certificate	19276-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	19276-Conflict-of-interest statement.pdf
Copyright License Agreement	19276-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	19276-Language certificate.pdf
Peer-review Report	19276-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19276-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19276-Scientific misconduct check.pdf
Scientific Editor Work List	19276-Scientific editor work list.pdf