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Articles Published Processes
3/23/2016 4:26:00 PM | Browse: 991 | Download: 1948
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Received |
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2015-05-03 11:18 |
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Peer-Review Started |
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2015-05-09 12:27 |
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To Make the First Decision |
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2015-09-09 17:01 |
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Return for Revision |
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2015-09-13 13:22 |
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Revised |
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2015-10-06 00:53 |
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Second Decision |
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2015-11-19 09:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-12-01 08:29 |
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Articles in Press |
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2015-12-01 08:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-03-08 17:29 |
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Publish the Manuscript Online |
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2016-03-23 16:22 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Study |
| Article Title |
Donor preoperative oxygen delivery and post-extubation hypoxia impact donation after circulatory death hypoxic cholangiopathy
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Thomas J Chirichella, C Michael Dunham, Michael A Zimmerman, Elise M Phelan, M Susan Mandell, Kendra D Conzen, Stephen E Kelley, Trevor L Nydam, Thomas E Bak, Igal Kam and Michael E Wachs |
| Funding Agency and Grant Number |
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| Corresponding Author |
Thomas J Chirichella, MD, Transplantation Fellow, Division of Transplant Surgery, 1635 Aurora Ct., 7th Floor, University of Colorado Hospital, Aurora, CO 80045, United States. tchirichella@gmail.com
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| Key Words |
Orthotopic liver transplantation; Ischemic cholangiopathy; Hypoxic cholangiopathy; Donation after circulatory death; Biliary complications; Reperfusion injury |
| Core Tip |
Cholangiopathy is a common and devastating clinical complication developing in recipients following donation after circulatory death liver transplantation. Numerous published investigations have attempted to link the hemodynamic instability and hypoxemia following withdrawal of life support to the development of cholangiopathy, without success. Our research indicates that cholangiopathy is linked to the magnitude of hypoxemic, ischemic, and anemic hypoxia transpiring after life support withdrawal and can be represented by a donor hypoxia score. We recommend that the historically utilized nomenclature of ischemic cholangiopathy be replaced using a more physiologic-based and expansive term, hypoxic cholangiopathy.
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| Publish Date |
2016-03-23 16:22 |
| Citation |
Chirichella TJ, Dunham CM, Zimmerman MA, Phelan EM, Mandell MS, Conzen KD, Kelley SE, Nydam TL, Bak TE, Kam I, Wachs ME. Donor preoperative oxygen delivery and post-extubation hypoxia impact donation after circulatory death hypoxic cholangiopathy. World J Gastroenterol 2016; 22(12): 3392-3403 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i12/3392.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i12.3392 |
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