Publication Name	World Journal of Gastroenterology
Manuscript ID	19389
Country	China

Received	2015-05-06 08:19
Peer-Review Started	2015-05-11 11:29
To Make the First Decision	2015-07-10 14:35
Return for Revision	2015-07-13 19:08
Revised	2015-07-20 12:30
Second Decision	2015-09-13 22:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-09-15 13:42
Articles in Press	2015-09-15 13:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-11-04 15:38
Publish the Manuscript Online	2015-11-18 12:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Cholestasis, ascites and pancytopenia in an immunocompetent adult with severe cytomegalovirus hepatitis
Manuscript Source	Unsolicited Manuscript
All Author List	Jun-Yan Qian, Xiao-Yin Bai, Yun-Lu Feng, Wen-Jia Zhu, Fang Yao, Jing-Nan Li, Ai-Ming Yang, Fang Li and Jia-Ming Qian
Funding Agency and Grant Number
Corresponding Author	Yun-Lu Feng, MD, Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Dongcheng District, Beijing 100730, China. yunluf@gmail.com
Key Words	Cytomegalovirus hepatitis; Cholestasis; Ascites; Pancytopenia; Immunocompetent adult
Core Tip	Human cytomegalovirus (CMV) can establish lifelong latency after primary infection. It also leads to severe disease in immunocompromised patients. However, CMV infection in immunocompetent patients is usually asymptomatic and severe organ damage is rarely reported. Here, we report an immunocompetent patient with a unique presentation of severe CMV hepatitis manifested by cholestasis, ascites and pancytopenia. The patient was asymptomatic with normal liver function and negative CMV DNA after two weeks of antiviral therapy. It is suggested that testing for CMV should be carried out, even in patients with normal immune status, presenting with severe liver damage or cholestasis.
Publish Date	2015-11-18 12:39
Citation	Qian JY, Bai XY, Feng YL, Zhu WJ, Yao F, Li JN, Yang AM, Li F, Qian JM. Cholestasis, ascites and pancytopenia in an immunocompetent adult with severe cytomegalovirus hepatitis. World J Gastroenterol 2015; 21(43): 12505-12509
URL	http://www.wjgnet.com/1007-9327/full/v21/i43/12505.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i43.12505

Full Article (PDF)	WJG-21-12505.pdf
Full Article (Word)	WJG-21-12505.doc
Manuscript File	19389-Review.doc
Answering Reviewers	19389-Answering reviewers.pdf
Audio Core Tip	19389-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19389-Conflict-of-interest statement.pdf
Copyright License Agreement	19389-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	19389-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	19389-Language certificate.PDF
Peer-review Report	19389-Peer-review(s).pdf
Scientific Misconduct Check	19389-Scientific misconduct check.pdf
Scientific Editor Work List	19389-Scientific editor work list.pdf