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Articles Published Processes
11/24/2015 3:55:00 PM | Browse: 1220 | Download: 3045
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Received |
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2015-05-06 16:35 |
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Peer-Review Started |
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2015-05-07 18:16 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2015-06-07 18:03 |
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Revised |
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2015-06-17 15:22 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2015-07-27 20:30 |
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Second Decision by Editor-in-Chief |
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2015-07-29 14:58 |
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Final Decision by Editorial Office Director |
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2015-09-02 15:15 |
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Articles in Press |
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2015-09-02 15:16 |
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Edit the Manuscript by Language Editor |
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2015-09-27 08:19 |
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Typeset the Manuscript |
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2015-11-04 15:50 |
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Publish the Manuscript Online |
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2015-11-18 12:39 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Virology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Relationship between virological response and FIB-4 index in chronic hepatitis B patients with entecavir therapy
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ni Li, Jing-Hang Xu, Min Yu, Sa Wang, Chong-Wen Si and Yan-Yan Yu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Science and Technology Major Project |
2012ZX10002003 |
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| Corresponding Author |
Yan-yan Yu, PhD, Professor, Department of Infectious Diseases, Peking University First Hospital, No. 8, Xi Shi Ku street, Xicheng District, Beijing 100034, China. yyy@bjmu.edu.cn |
| Key Words |
Chronic hepatitis B; Hepatitis B virus DNA; Entecavir; Partial virological response; Liver fibrosis; FIB-4 index |
| Core Tip |
Long-term entecavir therapy for patients with chronic hepatitis B (CHB) can result in histological improvement and regression of fibrosis substantially. However, the relationship between the serum low level hepatitis B virus (HBV) DNA and fibrosis is unclear for CHB patients with partial virological response to entecavir. Our study found that although the cumulative probabilities of HBV DNA response showed a significant difference between hepatitis B e antigen-positive CHB patients with complete virological response and partial virological response to 144 wk of entecavir treatment, long-term low level HBV DNA did not deter-iorate the FIB-4, which was used to evaluate liver fibrosis, by the end of three years.
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| Publish Date |
2015-11-18 12:39 |
| Citation |
Li N, Xu JH, Yu M, Wang S, Si CW, Yu YY. Relationship between virological response and FIB-4 index in chronic hepatitis B patients with entecavir therapy. World J Gastroenterol 2015; 21(43): 12421-12429 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i43/12421.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i43.12421 |
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