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11/24/2015 3:55:00 PM | Browse: 935 | Download: 1824
Publication Name World Journal of Gastroenterology
Manuscript ID 19399
Country/Territory China
Received
2015-05-06 16:35
Peer-Review Started
2015-05-07 18:16
To Make the First Decision
2015-06-02 15:58
Return for Revision
2015-06-07 18:03
Revised
2015-06-17 15:22
Second Decision
2015-07-27 20:30
Accepted by Journal Editor-in-Chief
2015-07-29 14:58
Accepted by Company Editor-in-Chief
2015-09-02 15:15
Articles in Press
2015-09-02 15:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-09-27 08:19
Typeset the Manuscript
2015-11-04 15:50
Publish the Manuscript Online
2015-11-18 12:39
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Virology
Manuscript Type Retrospective Study
Article Title Relationship between virological response and FIB-4 index in chronic hepatitis B patients with entecavir therapy
Manuscript Source Unsolicited Manuscript
All Author List Ni Li, Jing-Hang Xu, Min Yu, Sa Wang, Chong-Wen Si and Yan-Yan Yu
Funding Agency and Grant Number
Funding Agency Grant Number
National Science and Technology Major Project 2012ZX10002003
Corresponding Author Yan-yan Yu, PhD, Professor, Department of Infectious Diseases, Peking University First Hospital, No. 8, Xi Shi Ku street, Xicheng District, Beijing 100034, China. yyy@bjmu.edu.cn
Key Words Chronic hepatitis B; Hepatitis B virus DNA; Entecavir; Partial virological response; Liver fibrosis; FIB-4 index
Core Tip Long-term entecavir therapy for patients with chronic hepatitis B (CHB) can result in histological improvement and regression of fibrosis substantially. However, the relationship between the serum low level hepatitis B virus (HBV) DNA and fibrosis is unclear for CHB patients with partial virological response to entecavir. Our study found that although the cumulative probabilities of HBV DNA response showed a significant difference between hepatitis B e antigen-positive CHB patients with complete virological response and partial virological response to 144 wk of entecavir treatment, long-term low level HBV DNA did not deter-iorate the FIB-4, which was used to evaluate liver fibrosis, by the end of three years.
Publish Date 2015-11-18 12:39
Citation Li N, Xu JH, Yu M, Wang S, Si CW, Yu YY. Relationship between virological response and FIB-4 index in chronic hepatitis B patients with entecavir therapy. World J Gastroenterol 2015; 21(43): 12421-12429
URL http://www.wjgnet.com/1007-9327/full/v21/i43/12421.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i43.12421
Full Article (PDF) WJG-21-12421.pdf
Full Article (Word) WJG-21-12421.doc
Manuscript File 19399-Review.doc
Answering Reviewers 19399-Answering reviewers.pdf
Audio Core Tip 19399-Audio core tip.wav
Biostatistics Review Certificate 19399-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 19399-Conflict-of-interest statement.pdf
Copyright License Agreement 19399-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 19399-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 19399-Language certificate.pdf
Peer-review Report 19399-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 19399-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 19399-Scientific misconduct check.pdf
Scientific Editor Work List 19399-Scientific editor work list.pdf