Publication Name	World Journal of Gastroenterology
Manuscript ID	19412
Country	United States

Received	2015-05-07 08:54
Peer-Review Started	2015-05-11 12:53
To Make the First Decision	2015-06-02 15:10
Return for Revision	2015-06-04 14:44
Revised	2015-06-18 11:41
Second Decision	2015-07-07 22:28
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-07-08 17:49
Articles in Press	2015-07-08 17:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-08-10 16:45
Publish the Manuscript Online	2015-08-28 17:04

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Review
Article Title	Non-functional neuroendocrine tumors of the pancreas: Advances in diagnosis and management
Manuscript Source	Invited Manuscript
All Author List	Jordan M Cloyd and George A Poultsides
Funding Agency and Grant Number
Corresponding Author	George A Poultsides, MD, Department of Surgery, Stanford University, 300 Pasteur Dr, H3680, Stanford, CA 94305, United States. gpoultsides@stanford.edu
Key Words	Pancreas; Neuroendocrine tumor; Neuroendocrine carcinoma; Islet cell; Octreotide
Core Tip	Pancreatic neuroendocrine tumors (PNETs) are a fascinating and diverse group of neoplasms. While the clinical features of functional PNETs are frequently discussed, the majority of PNETs are actually non-functional. Although typically slow growing, tumors with more aggressive biology may progress to unresectable metastatic disease. Surgery should be considered for all patients for whom complete resection is possible, while liver directed therapies are useful for managing hepatic metastases. For patients with progressive metastatic disease, strong evidence supports the use of somatostatin analogues, everolimus and sunitinib in prolonging survival. The purpose of this article is to provide a comprehensive review of NF-PNETs.
Publish Date	2015-08-28 17:04
Citation	Cloyd JM, Poultsides GA. Non-functional neuroendocrine tumors of the pancreas: Advances in diagnosis and management. World J Gastroenterol 2015; 21(32): 9512-9525
URL	http://www.wjgnet.com/1007-9327/full/v21/i32/9512.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i32.9512

Full Article (PDF)	WJG-21-9512.pdf
Full Article (Word)	WJG-21-9512.doc
Manuscript File	19412-Review.docx
Answering Reviewers	19412-Answering reviewers.pdf
Audio Core Tip	19412-Audio core tip.wav
Conflict-of-Interest Disclosure Form	19412-Conflict-of-interest statement.pdf
Copyright License Agreement	19412-Copyright assignment.pdf
Peer-review Report	19412-Peer-review(s) .pdf
Scientific Misconduct Check	19412-Scientific misconduct check.pdf
Scientific Editor Work List	19412-Scientific editor work list.pdf