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9/24/2015 6:44:00 PM | Browse: 387 | Download: 911
Publication Name World Journal of Transplantation
Manuscript ID 19435
Country of Manuscript Source Italy
Received
2015-05-08 08:10
Peer-Review Started
2015-05-09 19:51
To Make the First Decision
2015-06-03 14:55
Return for Revision
2015-06-09 11:30
Revised
2015-06-12 06:19
Second Decision
2015-06-29 08:21
Accepted by Journal Editor-in-Chief
2015-06-30 20:28
Accepted by Company Editor-in-Chief
2015-07-08 15:33
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-09-17 15:37
Publish the Manuscript Online
2015-09-24 18:44
ISSN 2220-3230 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Hematology
Manuscript Type Retrospective Study
Article Title Cytomegalovirus reactivation after autologous stem cell transplantation in myeloma and lymphoma patients: A single-center study
Manuscript Source Invited Manuscript
All Author List Francesco Marchesi, Fulvia Pimpinelli, Svitlana Gumenyuk, Daniela Renzi, Francesca Palombi, Francesco Pisani, Atelda Romano, Antonio Spadea, Elena Papa, Marco Canfora, Fabrizio Ensoli and Andrea Mengarelli
Funding Agency and Grant Number
Corresponding author Francesco Marchesi, MD, Hematology and Stem Cell Transplantation Unit, Regina Elena National Cancer Institute, Via E. Chianesi 53, 00144 Rome, Italy. marchesi.francesco@tiscali.it
Keywords Cytomegalovirus; Autologous hematopoietic stem cell transplantation; Lymphoma; Myeloma; HBcIgG seropositivity; Transplant-related mortality
Core Tip Data about cytomegalovirus (CMV) reactivation in autologous hematopoietic stem cell transplantation (ASCT) are limited. We performed a retrospective observational study on 327 autografts consecutively performed for lymphoma (n = 126) or myeloma (n = 201) patients in our Institution. Aim of the study was to determine the incidence of and the risk factors for CMV symptomatic infection and/or end-organ disease, defined according to published recommendations, and the impact on Transplant-Related Mortality. Our data show that a symptomatic CMV infection can occur in about 11% of adult patients with lymphoma or myeloma undergoing ASCT. Most of cases of CMV reactivation are easily manageable but it can be a potentially life-threatening complication. As for risk factors, a pre-transplant HBcIgG seropositivity and a diagnosis of T-cell non-Hodgkin’s lymphoma should be considered as independent risk factors for CMV reactivation after ASCT.
Publish Date 2015-09-24 18:44
Citation Marchesi F, Pimpinelli F, Gumenyuk S, Renzi D, Palombi F, Pisani F, Romano A, Spadea A, Papa E, Canfora M, Ensoli F, Mengarelli A. Cytomegalovirus reactivation after autologous stem cell transplantation in myeloma and lymphoma patients: A single-center study. World J Transplant 2015; 5(3): 129-136
Url http://www.wjgnet.com/2220-3230/full/v5/i3/129.htm
DOI http://dx.doi.org/10.5500/wjt.v5.i3.129
Full Article (PDF) WJT-5-129.pdf
Full Article (Word) WJT-5-129.doc
Manuscript File 19435-Review.docx
Answering Reviewers 19435-Answering reviewers.pdf
Audio Core Tip 19435-Audio core tip.m4a
Biostatistics Review Certificate 19435-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 19435-Conflict-of-interest statement.pdf
Copyright License Agreement 19435-Copyright assignment.pdf
Data Sharing Statement 19435-Data sharing statement.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20150508044737.docx
Institutional Review Board Approval Form or Document 19435-Istitutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 19435-Language certificate.pdf
Peer-review Report 19435-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 19435-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 19435-Scientific misconduct check.pdf
Scientific Editor Work List 19435-Scientific editor work list.pdf