Publication Name	World Journal of Transplantation
Manuscript ID	19435
Country	Italy

Received	2015-05-08 08:10
Peer-Review Started	2015-05-09 19:51
To Make the First Decision	2015-06-03 14:55
Return for Revision	2015-06-09 11:30
Revised	2015-06-12 06:19
Second Decision	2015-06-29 08:21
Accepted by Journal Editor-in-Chief	2015-06-30 20:28
Accepted by Company Editor-in-Chief	2015-07-08 15:33
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-09-17 15:37
Publish the Manuscript Online	2015-09-24 18:44

ISSN	2220-3230 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Hematology
Manuscript Type	Retrospective Study
Article Title	Cytomegalovirus reactivation after autologous stem cell transplantation in myeloma and lymphoma patients: A single-center study
Manuscript Source	Invited Manuscript
All Author List	Francesco Marchesi, Fulvia Pimpinelli, Svitlana Gumenyuk, Daniela Renzi, Francesca Palombi, Francesco Pisani, Atelda Romano, Antonio Spadea, Elena Papa, Marco Canfora, Fabrizio Ensoli and Andrea Mengarelli
Funding Agency and Grant Number
Corresponding Author	Francesco Marchesi, MD, Hematology and Stem Cell Transplantation Unit, Regina Elena National Cancer Institute, Via E. Chianesi 53, 00144 Rome, Italy. marchesi.francesco@tiscali.it
Key Words	Cytomegalovirus; Autologous hematopoietic stem cell transplantation; Lymphoma; Myeloma; HBcIgG seropositivity; Transplant-related mortality
Core Tip	Data about cytomegalovirus (CMV) reactivation in autologous hematopoietic stem cell transplantation (ASCT) are limited. We performed a retrospective observational study on 327 autografts consecutively performed for lymphoma (n = 126) or myeloma (n = 201) patients in our Institution. Aim of the study was to determine the incidence of and the risk factors for CMV symptomatic infection and/or end-organ disease, defined according to published recommendations, and the impact on Transplant-Related Mortality. Our data show that a symptomatic CMV infection can occur in about 11% of adult patients with lymphoma or myeloma undergoing ASCT. Most of cases of CMV reactivation are easily manageable but it can be a potentially life-threatening complication. As for risk factors, a pre-transplant HBcIgG seropositivity and a diagnosis of T-cell non-Hodgkin’s lymphoma should be considered as independent risk factors for CMV reactivation after ASCT.
Publish Date	2015-09-24 18:44
Citation	Marchesi F, Pimpinelli F, Gumenyuk S, Renzi D, Palombi F, Pisani F, Romano A, Spadea A, Papa E, Canfora M, Ensoli F, Mengarelli A. Cytomegalovirus reactivation after autologous stem cell transplantation in myeloma and lymphoma patients: A single-center study. World J Transplant 2015; 5(3): 129-136
URL	http://www.wjgnet.com/2220-3230/full/v5/i3/129.htm
DOI	http://dx.doi.org/10.5500/wjt.v5.i3.129

Full Article (PDF)	WJT-5-129.pdf
Full Article (Word)	WJT-5-129.doc
Manuscript File	19435-Review.docx
Answering Reviewers	19435-Answering reviewers.pdf
Audio Core Tip	19435-Audio core tip.m4a
Biostatistics Review Certificate	19435-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	19435-Conflict-of-interest statement.pdf
Copyright License Agreement	19435-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20150508044737.docx
Institutional Review Board Approval Form or Document	19435-Istitutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	19435-Language certificate.pdf
Peer-review Report	19435-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19435-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19435-Scientific misconduct check.pdf
Scientific Editor Work List	19435-Scientific editor work list.pdf