Publication Name	World Journal of Virology
Manuscript ID	19439
Country	China

Received	2015-05-08 16:22
Peer-Review Started	2015-05-09 20:36
First Decision by Editorial Office Director
Return for Revision	2015-06-25 13:47
Revised	2015-06-29 09:42
Publication Fee Transferred
Second Decision by Editor	2015-10-08 13:26
Second Decision by Editor-in-Chief	2015-10-09 13:27
Final Decision by Editorial Office Director	2015-12-02 14:34
Articles in Press	2015-12-02 14:34
Edit the Manuscript by Language Editor	2015-12-11 19:25
Typeset the Manuscript	2016-01-25 12:10
Publish the Manuscript Online	2016-02-01 13:23

ISSN	2220-3249 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Virology
Manuscript Type	Basic Study
Article Title	Pathogenicity of a currently circulating Chinese variant pseudorabies virus in pigs
Manuscript Source	Invited Manuscript
All Author List	Qing-Yuan Yang, Zhe Sun, Fei-Fei Tan, Ling-Hua Guo, Yu-Zhou Wang, Juan Wang, Zhi-Yan Wang, Li-Lin Wang, Xiang-Dong Li, Yan Xiao and Ke-Gong Tian
Funding Agency and Grant Number
Corresponding Author	Dr. Ke-Gong Tian, National Research Center for Veterinary Medicine, Cuiwei Road, High-Tech District, Luoyang 471003, Henan Province, China. tiankg@263.net
Key Words	Pseudorabies virus; Pathogenicity; Virus variant; Gross pathology; Histopathology
Core Tip	Pseudorabies virus (PRV) variant HN1201 has pathogenicity in 35 to 127-d old pigs via intrana-sal inoculation at 107 TCID50. Intranasal inoculation is more efficient than intramuscular inoculation for PRV challenge. PRV variant HN1201 showed higher patho-genic ability, as shown by the more severe clinical symptoms, pathological lesions, and abundant antigen distribution in extensive organs than the classical PRV Fa strain.
Publish Date	2016-02-01 13:23
Citation	Yang QY, Sun Z, Tan FF, Guo LH, Wang YZ, Wang J, Wang ZY, Wang LL, Li XD, Xiao Y, Tian KG. Pathogenicity of a currently circulating Chinese variant pseudorabies virus in pigs. World J Virol 2016; 5(1): 23-30
URL	http://www.wjgnet.com/2220-3249/full/v5/i1/23.htm
DOI	http://dx.doi.org/10.5501/wjv.v5.i1.23

Full Article (PDF)	WJV-5-23.pdf
Full Article (Word)	WJV-5-23.doc
Manuscript File	19439-Review.doc
Answering Reviewers	19439-Answering reviewers.pdf
Audio Core Tip	19439-Audio core tip.mp3
Biostatistics Review Certificate	19439-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	19439-Conflict-of-interest statement.pdf
Copyright License Agreement	19439-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	19439-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	19439-Institutional review board statement.pdf
Supplementary Material	19439-Supplementary material.docx
Peer-review Report	19439-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19439-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19439-Scientific misconduct check.pdf
Scientific Editor Work List	19439-Scientific editor work list.pdf