Publication Name	World Journal of Gastroenterology
Manuscript ID	19441
Country	New Zealand

Received	2015-05-08 16:24
Peer-Review Started	2015-05-11 16:10
First Decision by Editorial Office Director
Return for Revision	2015-06-04 14:58
Revised	2015-06-19 06:51
Publication Fee Transferred
Second Decision by Editor	2015-09-28 16:03
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2015-09-30 10:03
Articles in Press	2015-09-30 10:04
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-08 18:20
Publish the Manuscript Online	2015-10-23 15:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Are faecal markers good indicators of mucosal healing in inflammatory bowel disease?
Manuscript Source	Invited Manuscript
All Author List	Gudula JAM Boon, Andrew S Day, Chris J Mulder and Richard B Gearry
Funding Agency and Grant Number
Corresponding Author	Richard B Gearry, Professor, Departments of Medicine, University of Otago, PO Box 4345, Christchurch 8140, New Zealand. richard.gearry@cdhb.govt.nz
Key Words	Crohn’s disease; Ulcerative colitis; Mucosal healing; Faecal calprotectin; Inflammatory bowel disease; Faecal lactoferrin
Core Tip	With regard to mucosal inflammation and response to therapy in Crohn’s disease and ulcerative colitis patients, mucosal healing may be a more reliable target for treatment than clinical and biochemical assessment. The available studies in this review show that faecal biomarkers are promising non-invasive indicators of mucosal healing and they could be an appropriate surrogate to endoscopy (the gold standard) in inflammatory bowel diseases patients. However, due to a wide variability in the use of clinical indices and marker cut offs, it’s difficult to compare their performances. Moreover, a clear definition of mucosal healing is needed.
Publish Date	2015-10-23 15:45
Citation	Boon GJAM, Day AS, Mulder CJ, Gearry RB. Are faecal markers good indicators of mucosal healing in inflammatory bowel disease? World J Gastroenterol 2015; 21(40): 11469-11480
URL	http://www.wjgnet.com/1007-9327/full/v21/i40/11469.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i40.11469

Full Article (PDF)	WJG-21-11469.pdf
Full Article (Word)	WJG-21-11469.doc
Manuscript File	19441-Review.docx
Answering Reviewers	19441-Answering reviewers.pdf
Audio Core Tip	19441-Audio core tip.m4a
Biostatistics Review Certificate	19441-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	19441-Conflict-of-interest statement.pdf
Copyright License Agreement	19441-Copyright assignment.pdf
Peer-review Report	19441-Peer-review(s).pdf
Scientific Misconduct Check	19441-Scientific misconduct check.pdf
Scientific Editor Work List	19441-Scientific editor work list.pdf