Publication Name	World Journal of Radiology
Manuscript ID	19450
Country	Japan

Received	2015-05-08 16:39
Peer-Review Started	2015-05-09 20:52
To Make the First Decision	2015-07-27 18:39
Return for Revision	2015-08-01 18:50
Revised	2015-08-13 17:35
Second Decision	2015-09-28 14:32
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-10-13 17:09
Articles in Press	2015-10-13 17:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-22 21:09
Publish the Manuscript Online	2015-12-28 08:56

ISSN	1949-8470 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Urology & Nephrology
Manuscript Type	Retrospective Study
Article Title	Recovery of serum testosterone following neoadjuvant and adjuvant androgen deprivation therapy in men treated with prostate brachytherapy
Manuscript Source	Invited Manuscript
All Author List	Hideyasu Tsumura, Takefumi Satoh, Hiromichi Ishiyama, Shuhei Hirano, Ken-ichi Tabata, Shinji Kurosaka, Kazumasa Matsumoto, Tetsuo Fujita, Masashi Kitano, Shiro Baba, Kazushige Hayakawa and Masatsugu Iwamura
Funding Agency and Grant Number
Corresponding Author	Hideyasu Tsumura, MD, Department of Urology, Kitasato University School of Medicine, 1-15-1 Kitasato Minami-ku, Sagamihara 252-0374, Japan. tsumura@med.kitasato-u.ac.jp
Key Words	Androgen deprivation; Gonadotropin-releasing hormone agonist; Prostate brachytherapy; Prostate cancer; Testosterone
Core Tip	We evaluated the time course of testosterone recovery and the prognostic factors associated with prolonged testosterone recovery after the cessation of long-term (≥ 36 mo) androgen deprivation therapy in patients treated with brachytherapy. Five years after cessation, 22.6% of patients maintained a castrate testosterone level. We should consider this delay when determining therapeutic effects. Lower testosterone levels at cessation were significantly associated with prolonged testosterone recovery.
Publish Date	2015-12-28 08:56
Citation	Tsumura H, Satoh T, Ishiyama H, Hirano S, Tabata K, Kurosaka S, Matsumoto K, Fujita T, Kitano M, Baba S, Hayakawa K, Iwamura M. Recovery of serum testosterone following neoadjuvant and adjuvant androgen deprivation therapy in men treated with prostate brachytherapy. World J Radiol 2015; 7(12): 494-500
URL	http://www.wjgnet.com/1949-8470/full/v7/i12/494.htm
DOI	http://dx.doi.org/10.4329/wjr.v7.i12.494

Full Article (PDF)	WJR-7-494.pdf
Full Article (Word)	WJR-7-494.doc
Manuscript File	19450-Review.docx
Answering Reviewers	19450-Answering reviewers.pdf
Audio Core Tip	19450-Audio core tip.MP3
Biostatistics Review Certificate	19450-Biostatistic statement.pdf
Conflict-of-Interest Disclosure Form	19450-Conflict-of-interest statement.pdf
Copyright License Agreement	19450-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	19450-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	Editing_Certificate_20150508160016.pdf
Peer-review Report	19450-Peer-review(s).pdf
Scientific Misconduct Check	19450-Scientific misconduct check.pdf
Scientific Editor Work List	19450-Scientific editor work list.pdf