Publication Name	World Journal of Methodology
Manuscript ID	19473
Country	Iran

Received	2015-05-09 13:17
Peer-Review Started	2015-05-11 17:48
To Make the First Decision	2015-07-06 15:54
Return for Revision	2015-07-09 10:08
Revised	2015-08-05 07:42
Second Decision	2015-11-23 17:51
Accepted by Journal Editor-in-Chief	2015-11-23 18:13
Accepted by Executive Editor-in-Chief	2015-12-02 14:34
Articles in Press	2015-12-02 14:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-03 13:15
Publish the Manuscript Online	2015-12-15 10:10

ISSN	2222-0682 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Microbiology
Manuscript Type	Basic Study
Article Title	Recombinant outer membrane protein F-B subunit of LT protein as a prophylactic measure against Pseudomonas aeruginosa burn infection in mice
Manuscript Source	Invited Manuscript
All Author List	Hassan Heydari Farsani, Iraj Rasooli, Seyed Latif Mousavi Gargari, Shahram Nazarian and Shakiba Darwish Alipour Astaneh
Funding Agency and Grant Number
Corresponding Author	Iraj Rasooli, Professor, Department of Biology, Shahed University, Tehran-Qom Express Way, Opposite Imam Khomeini’s Shrine, Tehran 3319118651, Iran. rasooli@shahed.ac.ir
Key Words	Pseudomonas aeruginosa; Outer membrane protein F; B subunit of LT; Immunization; Burn
Core Tip	Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogen that infects hospitalized, burned and immunosuppressed patients. Vaccination of high-risk groups may reduce the incidence and spread of infection. In this study outer membrane protein F (OprF) and fusion genes containing OprF and B subunit of LT were cloned and expressed. The proteins were administered to the experimental mice challenged at the burn site with lethal dose of P. aeruginosa. Significant protection was noted in immunized animals.
Publish Date	2015-12-15 10:10
Citation	Farsani HH, Rasooli I, Gargari SLM, Nazarian S, Astaneh SDA. Recombinant outer membrane protein F-B subunit of LT protein as a prophylactic measure against Pseudomonas aeruginosa burn infection in mice. World J Methodol 2015; 5(4): 230-237
URL	http://www.wjgnet.com/2222-0682/full/v5/i4/230.htm
DOI	http://dx.doi.org/10.5662/wjm.v5.i4.230

Full Article (PDF)	WJM-5-230.pdf
Full Article (Word)	WJM-5-230.doc
Manuscript File	19473-Review.doc
Answering Reviewers	19473-Answering reviewers.pdf
Audio Core Tip	19473-Audio core tip.mp3
Biostatistics Review Certificate	19473-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	19473-Conflict-of-interest statement.pdf
Copyright License Agreement	19473-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	19473-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	19473-Institutional review board statement.pdf
Peer-review Report	19473-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19473-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19473-Scientific misconduct check.pdf
Scientific Editor Work List	19473-Scientific editor work list.pdf