Publication Name	World Journal of Cardiology
Manuscript ID	19513
Country	Japan

Received	2015-05-11 09:51
Peer-Review Started	2015-05-11 17:39
To Make the First Decision	2015-06-03 14:28
Return for Revision	2015-06-09 09:57
Revised	2015-06-15 09:07
Second Decision	2015-06-15 18:05
Accepted by Journal Editor-in-Chief	2015-06-15 22:03
Accepted by Company Editor-in-Chief	2015-06-19 18:05
Articles in Press	2015-06-19 18:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-08-14 19:23
Publish the Manuscript Online	2015-08-27 11:20

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Review
Article Title	Adipose tissue-derived stem cells as a therapeutic tool for cardiovascular disease
Manuscript Source	Invited Manuscript
All Author List	Etsu Suzuki, Daishi Fujita, Masao Takahashi, Shigeyoshi Oba and Hiroaki Nishimatsu
Funding Agency and Grant Number
Corresponding Author	Etsu Suzuki, MD, PhD, Institute of Medical Science, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki 216-8512, Japan. esuzuki-tky@umin.ac.jp
Key Words	Adipose tissue-derived stem cells; Cardio­vascular disease; Acute myocardial infarction; Ischemic cardiomyopathy; Hindlimb ischemia; Stroke
Core Tip	Adipose tissue-derived stem cells (ADSCs) have been used for the treatment of cardiovascular disease with the efficacy of ADSC implantation demonstrated in animal models. However, the mechanisms under-lying the capacity of ADSCs for regenerating the car-diovascular system remain controversial. ADSCs may differentiate into blood vessels and cardiomyocytes, fuse with other cell types, obtaining the characteristics of those cells, and secrete paracrine factors that have proangiogenic and/or antiapoptotic activities. This review also discusses recently initiated clinical trials using autologous ADSCs.
Publish Date	2015-08-27 11:20
Citation	Suzuki E, Fujita D, Takahashi M, Oba S, Nishimatsu H. Adipose tissue-derived stem cells as a therapeutic tool for cardiovascular disease. World J Cardiol 2015; 7(8): 454-465
URL	http://www.wjgnet.com/1949-8462/full/v7/i8/454.htm
DOI	http://dx.doi.org/10.4330/wjc.v7.i8.454

Full Article (PDF)	WJC-7-454.pdf
Full Article (Word)	WJC-7-454.doc
Manuscript File	19513-Review.docx
Answering Reviewers	19513-Answering reviewers.pdf
Audio Core Tip	19513-Audio core tip.aif
Conflict-of-Interest Disclosure Form	19513-Conflict-of-interest statement.PDF
Copyright License Agreement	19513-Copyright assignment.pdf
Peer-review Report	19513-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19513-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19513-Scientific misconduct check.pdf
Scientific Editor Work List	19513-Scientific editor work list.pdf