Publication Name	World Journal of Hepatology
Manuscript ID	19579
Country	Japan

Received	2015-05-13 08:42
Peer-Review Started	2015-05-15 10:21
To Make the First Decision	2015-06-02 14:55
Return for Revision	2015-06-06 18:56
Revised	2015-06-18 18:19
Second Decision	2015-09-13 22:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-09-21 10:21
Articles in Press	2015-09-21 10:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-09-24 11:11
Publish the Manuscript Online	2015-10-19 16:02

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Antiviral therapy for chronic hepatitis B: Combination of nucleoside analogs and interferon
Manuscript Source	Invited Manuscript
All Author List	Satoru Hagiwara, Naoshi Nishida and Masatoshi Kudo
Funding Agency and Grant Number	Funding Agency Grant Number Japanese Society for the Promotion of Science 24590997 (to Nishida N) Smoking Research Foundation to Nishida N
Corresponding Author	Naoshi Nishida, MD, PhD, Department of Gastroenterology and Hepatology, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan. naoshi@med.kindai.ac.jp
Key Words	Hepatitis B virus; Interferon; Sequential therapy; Combination therapy; Nucleoside analog
Core Tip	For the suppression of emergence of hepato-cellular carcinoma, disappearance of hepatitis B s antigen (HBsAg) is necessary, which is an important goal for the treatment of chronic hepatitis B. In order to achieve HBsAg clearance, combination therapies with nucleoside analogs (NAs) and interferon (IFN) and sequential therapies with NAs administration followed by IFN therapy have been routinely employed. The combination of antiviral agents, and the appropriate selection of patients are critical to obtain a good response for HBsAg clearance.
Publish Date	2015-10-19 16:02
Citation	Hagiwara S, Nishida N, Kudo M. Antiviral therapy for chronic hepatitis B: Combination of nucleoside analogs and interferon. World J Hepatol 2015; 7(23): 2427-2431
URL	http://www.wjgnet.com/1948-5182/full/v7/i23/2427.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i23.2427

Full Article (PDF)	WJH-7-2427.pdf
Full Article (Word)	WJH-7-2427.doc
Manuscript File	19579-Review.doc
Answering Reviewers	19579-Answering reviewers.pdf
Audio Core Tip	19579-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19579-Conflict-of-interest statement.pdf
Copyright License Agreement	19579-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	19579-Language certificate.pdf
Peer-review Report	19579-Peer-review(s).pdf
Scientific Misconduct Check	19579-Scientific misconduct check.pdf
Scientific Editor Work List	19579-Scientific editor work list.pdf