Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	19597
Country	Italy

Received	2015-05-14 09:57
Peer-Review Started	2015-05-15 13:01
To Make the First Decision	2015-06-25 17:54
Return for Revision	2015-07-01 09:47
Revised	2015-07-15 16:21
Second Decision	2015-08-07 17:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-08-14 16:31
Articles in Press	2015-08-14 16:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-24 20:17
Publish the Manuscript Online	2015-11-17 08:51

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Gastric cancer: The times they are a-changin’
Manuscript Source	Invited Manuscript
All Author List	Maria Antonietta Satolli, Lucio Buffoni, Rosella Spadi and Ilaria Roato
Funding Agency and Grant Number	Funding Agency Grant Number CRT Foudation Italian Ministry of Health: Ricerca Sanitaria Finalizzata e Giovani Ricercatori 2009 GR 2009-1584485
Corresponding Author	Ilaria Roato, PhD, CeRMS, AOU Città della Salute e della Scienza di Torino, Department of Medical Science, University of Turin, Via Santena 5, 10126 Torino, Italy. roato78@libero.it
Key Words	Targeted therapy; Chemotherapy; Gastric cancer; Immunotherapy
Core Tip	Gastric cancer, despite its decrease in West Countries, remains one of the most common malignancies worldwide. The prognosis in the advanced setting is often poor even with a multidisciplinary approach, which aims to increase the patients’ survival. The molecular classification of four subtypes of gastric adenocarcinomas (The Cancer Genome Atlas project) allowed a better stratification of patients in clinical trials for targeted therapies. Biologic agents, modulating the immune checkpoints, seem to be the best promising therapeutic approach, opening new perspective for advanced gastric cancer treatment.
Publish Date	2015-11-17 08:51
Citation	Satolli MA, Buffoni L, Spadi R, Roato I. Gastric cancer: The times they are a-changin’. World J Gastrointest Oncol 2015; 7(11): 303-316
URL	http://www.wjgnet.com/1948-5204/full/v7/i11/303.htm
DOI	http://dx.doi.org/10.4251/wjgo.v7.i11.303

Full Article (PDF)	WJGO-7-303.pdf
Full Article (Word)	WJGO-7-303.doc
Manuscript File	19597-Review.doc
Answering Reviewers	19597-Answering reviewers.pdf
Audio Core Tip	19597-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19597-Conflict-of-interest statement.pdf
Copyright License Agreement	19597-Copyright assignment.pdf
Peer-review Report	19597-Peer-review(s).pdf
Scientific Misconduct Check	19597-Scientific misconduct check.pdf
Scientific Editor Work List	19597-Scientific editor work list.pdf