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Articles Published Processes
12/6/2015 1:18:00 PM | Browse: 1340 | Download: 2631
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Received |
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2015-05-16 14:16 |
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Peer-Review Started |
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2015-05-20 14:48 |
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To Make the First Decision |
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2015-06-19 18:05 |
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Return for Revision |
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2015-06-20 20:43 |
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Revised |
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2015-07-10 21:17 |
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Second Decision |
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2015-08-03 10:27 |
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Accepted by Journal Editor-in-Chief |
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2015-08-06 15:22 |
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Accepted by Executive Editor-in-Chief |
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2015-08-31 16:32 |
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Articles in Press |
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2015-08-31 16:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-11-23 17:30 |
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Publish the Manuscript Online |
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2015-12-06 13:18 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Dermatology |
| Manuscript Type |
Basic Study |
| Article Title |
Dextran sulfate sodium-induced acute colitis impairs dermal lymphatic function in mice
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Germaine D Agollah, Grace Wu, Ho-Lan Peng and Sunkuk Kwon |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| NIH/National Institute of Diabetes and Digestive and Kidney Disease |
P30 DK56338 (In part,to Kwon S) |
| Schissler Foundation Fellowship for Translational Studies of Common Human Diseases |
to Agollah GD |
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| Corresponding Author |
Sunkuk Kwon, PhD, Assistant Professor, Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, 1825 Pressler Street, SRB 330F, Houston, Texas 77030, United States. sunkuk.kwon@uth.tmc.edu |
| Key Words |
Dextran sulfate sodium; Colitis; Lymphatic system; Inflammation; Near-infrared fluorescence imaging |
| Core Tip |
Inflammatory bowel disease (IBD) is a systemic disease, as it is often associated with extra-intestinal manifestations, complications, and other autoimmune disorders. However, it is unknown whether dermal lymphatic function changes systemically in response to IBD. In this study, we employed near-infrared fluorescence imaging to characterize dermal lymphatic function and architecture in mice with dextran sulfate sodium (DSS)-induced acute colitis. Our results demonstrated impaired lymphatic function in mesenteric lymphatics accompanied by dilated lymphatic vessels and reduced lymphatic contractility in the skin of mice with DSS-induced acute colitis, indicating that DSS-induced acute colitis results in systemic lymphatic dysfunction. |
| Publish Date |
2015-12-06 13:18 |
| Citation |
Agollah GD, Wu G, Peng HL, Kwon S. Dextran sulfate sodium-induced acute colitis impairs dermal lymphatic function in mice. World J Gastroenterol 2015; 21(45): 12767-12777 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i45/12767.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i45.12767 |
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