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Articles Published Processes
3/23/2016 4:26:00 PM | Browse: 1266 | Download: 2169
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Received |
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2015-05-18 08:34 |
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Peer-Review Started |
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2015-05-20 18:01 |
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To Make the First Decision |
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2015-07-19 15:35 |
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Return for Revision |
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2015-07-22 19:49 |
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Revised |
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2015-09-30 01:50 |
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Second Decision |
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2015-11-19 09:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-12-01 08:55 |
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Articles in Press |
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2015-12-01 08:55 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-01-30 16:30 |
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Publish the Manuscript Online |
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2016-03-23 16:22 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Transplantation |
Manuscript Type |
Retrospective Study |
Article Title |
Two strategies for prevention of cytomegalovirus infections after liver transplantation
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Philipp Simon, Max Sasse, Sven Laudi, David Petroff, Michael Bartels, Udo X Kaisers and Sven Bercker |
Funding Agency and Grant Number |
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Corresponding Author |
Philipp Simon, MD, Department of Anesthesia and Intensive Care Medicine, Medical Faculty, University of Leipzig, Liebigstraße 20, 04103 Leipzig,
Germany. philipp.simon@medizin.uni-leipzig.de
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Key Words |
Transplantation; Liver; Cytomegalovirus; Preemptive; Prophylaxis; Valganciclovir; Therapy |
Core Tip |
This retrospective study compares a preemptive therapy to prophylaxis for cytomegalovirus (CMV) infection in 128 patients after liver transplan-tation (LTx). CMV infections are frequent and increase morbidity and mortality so that preventive strategies are routine procedures. The one-year mortality did not differ significantly between the preemptive (n = 68) and prophylaxis (n = 60) groups, though it was 10% (95%CI: 8%-28%, P = 0.31) higher for the former. Preemptive patients had a significantly higher rate of intervention with ganciclovir (23.5% vs 4.9%, P = 0.003). Our data suggest that CMV prophylaxis is superior to a preemptive strategy after LTx.
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Publish Date |
2016-03-23 16:22 |
Citation |
Simon P, Sasse M, Laudi S, Petroff D, Bartels M, Kaisers UX, Bercker S. Two strategies for prevention of cytomegalovirus infections after liver transplantation. World J Gastroenterol 2016; 22(12): 3412-3417 |
URL |
http://www.wjgnet.com/1007-9327/full/v22/i12/3412.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v22.i12.3412 |
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