Publication Name	World Journal of Gastroenterology
Manuscript ID	19702
Country	Germany

Received	2015-05-18 08:34
Peer-Review Started	2015-05-20 18:01
To Make the First Decision	2015-07-19 15:35
Return for Revision	2015-07-22 19:49
Revised	2015-09-30 01:50
Second Decision	2015-11-19 09:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-12-01 08:55
Articles in Press	2015-12-01 08:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-30 16:30
Publish the Manuscript Online	2016-03-23 16:22

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Transplantation
Manuscript Type	Retrospective Study
Article Title	Two strategies for prevention of cytomegalovirus infections after liver transplantation
Manuscript Source	Unsolicited Manuscript
All Author List	Philipp Simon, Max Sasse, Sven Laudi, David Petroff, Michael Bartels, Udo X Kaisers and Sven Bercker
Funding Agency and Grant Number
Corresponding Author	Philipp Simon, MD, Department of Anesthesia and Intensive Care Medicine, Medical Faculty, University of Leipzig, Liebigstraße 20, 04103 Leipzig, Germany. philipp.simon@medizin.uni-leipzig.de
Key Words	Transplantation; Liver; Cytomegalovirus; Preemptive; Prophylaxis; Valganciclovir; Therapy
Core Tip	This retrospective study compares a preemptive therapy to prophylaxis for cytomegalovirus (CMV) infection in 128 patients after liver transplan-tation (LTx). CMV infections are frequent and increase morbidity and mortality so that preventive strategies are routine procedures. The one-year mortality did not differ significantly between the preemptive (n = 68) and prophylaxis (n = 60) groups, though it was 10% (95%CI: 8%-28%, P = 0.31) higher for the former. Preemptive patients had a significantly higher rate of intervention with ganciclovir (23.5% vs 4.9%, P = 0.003). Our data suggest that CMV prophylaxis is superior to a preemptive strategy after LTx.
Publish Date	2016-03-23 16:22
Citation	Simon P, Sasse M, Laudi S, Petroff D, Bartels M, Kaisers UX, Bercker S. Two strategies for prevention of cytomegalovirus infections after liver transplantation. World J Gastroenterol 2016; 22(12): 3412-3417
URL	http://www.wjgnet.com/1007-9327/full/v22/i12/3412.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i12.3412

Full Article (PDF)	WJG-22-3412.pdf
Full Article (Word)	WJG-22-3412.doc
Manuscript File	19702-Review.doc
Answering Reviewers	19702-Answering reviewers.pdf
Audio Core Tip	19702-Audio core tip.mp3
Biostatistics Review Certificate	19702-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	19702-Conflict-of-interest statement.pdf
Copyright License Agreement	19702-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	19702-Institutional review board statement.pdf
Peer-review Report	19702-Peer-review(s).pdf
Scientific Misconduct Check	19702-Scientific misconduct check.pdf
Scientific Editor Work List	19702-Scientific editor work list.pdf