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11/3/2015 5:30:00 PM | Browse: 1064 | Download: 1721
Publication Name World Journal of Gastroenterology
Manuscript ID 19720
Country/Territory United States
Received
2015-05-18 15:43
Peer-Review Started
2015-05-20 08:50
To Make the First Decision
2015-07-13 15:19
Return for Revision
2015-07-17 16:53
Revised
2015-08-06 00:00
Second Decision
2015-09-13 22:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-09-15 13:47
Articles in Press
2015-09-15 13:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-10-21 17:05
Publish the Manuscript Online
2015-11-03 17:31
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Treatment-related gastrointestinal toxicities and advanced colorectal or pancreatic cancer: A critical update
Manuscript Source Invited Manuscript
All Author List Giuseppe Aprile, Karim Rihawi, Elisa De Carlo and Stephen T Sonis
Funding Agency and Grant Number
Corresponding Author Stephen T Sonis, DMD, DMSc, Divisions of Oral Medicine, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115, United States. ssonis@partners.org
Key Words Gastrointestinal toxicities; Oral mucositis; Diarrhea; Colorectal cancer; Pancreatic cancer
Core Tip Although extremely frequent, treatment-related gastrointestinal toxicities in patients with advanced colorectal cancer and pancreatic cancer are often underreported. As such, it is difficult to establish to what extent such toxicities affect both patient quality of life and cancer care costs. In our work we describe the main gastrointestinal toxicities as well as their pathophysiology and grading scales. Finally, based on the results of the main randomized clinical trials, we provide a critical update on their incidence with both chemotherapeutic agents and novel targeted drugs.
Publish Date 2015-11-03 17:31
Citation Aprile G, Rihawi K, De Carlo E, Sonis ST. Treatment-related gastrointestinal toxicities and advanced colorectal or pancreatic cancer: A critical update. World J Gastroenterol 2015; 21(41): 11793-11803
URL http://www.wjgnet.com/1007-9327/full/v21/i41/11793.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i41.11793
Full Article (PDF) WJG-21-11793.pdf
Full Article (Word) WJG-21-11793.doc
Manuscript File 19720-Review.doc
Answering Reviewers 19720-Answering reviewers.pdf
Audio Core Tip 19720-Audio core tip.wav
Conflict-of-Interest Disclosure Form 19720-Conflict-of-interest statement.pdf
Copyright License Agreement 19720-Copyright assignment.pdf
Supplementary Material Supplementary_Material_20150518154234.pdf
Peer-review Report 19720-Peer-review(s).pdf
Scientific Misconduct Check 19720-Scientific misconduct check.pdf
Scientific Editor Work List 19720-Scientific editor work list.pdf