Publication Name	World Journal of Immunology
Manuscript ID	19767
Country	United States

Received	2015-05-20 16:05
Peer-Review Started	2015-05-21 10:32
To Make the First Decision	2015-06-18 16:15
Return for Revision	2015-06-24 16:29
Revised	2015-06-28 15:35
Second Decision	2015-07-07 17:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-07-17 14:06
Articles in Press	2015-07-17 14:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-24 20:01
Publish the Manuscript Online	2015-08-04 10:49

ISSN	2219-2824 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Immunology
Manuscript Type	Editorial
Article Title	Antimicrobial lipids: Emerging effector molecules of innate host defense
Manuscript Source	Invited Manuscript
All Author List	Edith Porter, Daniel C Ma, Sandy Alvarez and Kym F Faull
Funding Agency and Grant Number	Funding Agency Grant Number National Institutes of Health 1R21AI55675 National Institutes of Health 1P20MD001824 National Institutes of Health 1SC1GM096916 National Institutes of Health 1S10RR023718-01A2 Cystic Fibrosis Foundation, Pilot Research PORTER12I0
Corresponding Author	Edith Porter, MD, Professor of Microbiology and Immunology, Department of Biological Sciences, California State University Los Angeles, 5151 State University Drive, Los Angeles, CA 90032, United States. eporter@calstatela.edu
Key Words	Atopic dermatitis; Cholesterol; Infectious disease; Cystic fibrosis; Mucosa
Core Tip	The antimicrobial properties of host derived lipids have become increasingly recognized. This review develops the concept of antimicrobial lipids (AMLs) as effectors of the innate immune response that work together with antimicrobial peptides to prevent infection, and highlights more recent reports on the regulation of AML production as well as bacterial resistance mechanisms. Furthermore, this review invites reconsideration of the interpretation of cholesteryl ester accumulation in macrophage lipid droplets in response to infection as a solely proinflammatory event, and proposes a direct antimicrobial role of lipid droplet- associated cholesteryl esters.
Publish Date	2015-08-04 10:49
Citation	Porter E, Ma DC, Alvarez S, Faull KF. Antimicrobial lipids: Emerging effector molecules of innate host defense. World J Immunol 2015; 5(2): 51-61
URL	http://www.wjgnet.com/2219-2824/full/v5/i2/51.htm
DOI	http://dx.doi.org/10.5411/wji.v5.i2.51

Full Article (PDF)	WJI-5-51.pdf
Full Article (Word)	WJI-5-51.doc
Manuscript File	19767-Review.docx
Answering Reviewers	19767-Answering reviewers.pdf
Audio Core Tip	19767-Audio core tip.wav
Conflict-of-Interest Disclosure Form	19767-Conflict-of-interest statement.pdf
Copyright License Agreement	19767-Copyright assignment.pdf
Peer-review Report	19767-Peer-review(s) .pdf
Scientific Misconduct Check	19767-Scientific misconduct check.pdf
Scientific Editor Work List	19767-Scientific editor work list .pdf