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8/4/2015 10:48:00 AM | Browse: 1383 | Download: 1516
Publication Name World Journal of Immunology
Manuscript ID 19767
Country/Territory United States
Received
2015-05-20 16:05
Peer-Review Started
2015-05-21 10:32
To Make the First Decision
2015-06-18 16:15
Return for Revision
2015-06-24 16:29
Revised
2015-06-28 15:35
Second Decision
2015-07-07 17:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-07-17 14:06
Articles in Press
2015-07-17 14:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-07-24 20:01
Publish the Manuscript Online
2015-08-04 10:49
ISSN 2219-2824 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Editorial
Article Title Antimicrobial lipids: Emerging effector molecules of innate host defense
Manuscript Source Invited Manuscript
All Author List Edith Porter, Daniel C Ma, Sandy Alvarez and Kym F Faull
Funding Agency and Grant Number
Funding Agency Grant Number
National Institutes of Health 1R21AI55675
National Institutes of Health 1P20MD001824
National Institutes of Health 1SC1GM096916
National Institutes of Health 1S10RR023718-01A2
Cystic Fibrosis Foundation, Pilot Research PORTER12I0
Corresponding Author Edith Porter, MD, Professor of Microbiology and Immunology, Department of Biological Sciences, California State University Los Angeles, 5151 State University Drive, Los Angeles, CA 90032, United States. eporter@calstatela.edu
Key Words Atopic dermatitis; Cholesterol; Infectious disease; Cystic fibrosis; Mucosa
Core Tip The antimicrobial properties of host derived lipids have become increasingly recognized. This review develops the concept of antimicrobial lipids (AMLs) as effectors of the innate immune response that work together with antimicrobial peptides to prevent infection, and highlights more recent reports on the regulation of AML production as well as bacterial resistance mechanisms. Furthermore, this review invites reconsideration of the interpretation of cholesteryl ester accumulation in macrophage lipid droplets in response to infection as a solely proinflammatory event, and proposes a direct antimicrobial role of lipid droplet- associated cholesteryl esters.
Publish Date 2015-08-04 10:49
Citation Porter E, Ma DC, Alvarez S, Faull KF. Antimicrobial lipids: Emerging effector molecules of innate host defense. World J Immunol 2015; 5(2): 51-61
URL http://www.wjgnet.com/2219-2824/full/v5/i2/51.htm
DOI http://dx.doi.org/10.5411/wji.v5.i2.51
Full Article (PDF) WJI-5-51.pdf
Full Article (Word) WJI-5-51.doc
Manuscript File 19767-Review.docx
Answering Reviewers 19767-Answering reviewers.pdf
Audio Core Tip 19767-Audio core tip.wav
Conflict-of-Interest Disclosure Form 19767-Conflict-of-interest statement.pdf
Copyright License Agreement 19767-Copyright assignment.pdf
Peer-review Report 19767-Peer-review(s) .pdf
Scientific Misconduct Check 19767-Scientific misconduct check.pdf
Scientific Editor Work List 19767-Scientific editor work list .pdf