Publication Name	World Journal of Gastroenterology
Manuscript ID	1985
Country	China

Received	2013-01-18 15:43
Peer-Review Started	2013-01-18 19:51
To Make the First Decision	2013-03-18 15:25
Return for Revision	2013-03-20 08:28
Revised	2013-04-03 17:05
Second Decision	2013-05-16 20:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-05-17 09:58
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-06-08 01:30
Typeset the Manuscript	2013-07-05 16:24
Publish the Manuscript Online	2013-07-13 17:01

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Association of Helicobacter pylori babA2 with peptic ulcer disease and gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Mo-Ye Chen, Cai-Yun He, Xue Meng and Yuan Yuan
Funding Agency and Grant Number	Funding Agency Grant Number National Basic Research Program of China, 973 Program 2010CB529304 Science and Technology Project of Liaoning province 2011225002 Science Project of Liaoning Province, China [2008]621
Corresponding Author	Yuan Yuan, Professor, Tumor Etiology and Screening Department of Cancer Institute and General Surgery, the First Affiliated Hospital of China Medical University, No. 155 North Nanjing Street, Heping District, Shenyang 110001, Liaoning Province, China. yyuan@mail.cmu.edu.cn
Key Words	Helicobacter pylori; babA2; Peptic ulcer; Gastric cancer; Risk
Core Tip	BabA encoded by babA2 gene is an outer member protein of Helicobacter pylori (H. pylori), which plays a key role in facilitating bacterial colonization in the stomach. The association between babA2 and H. pylori-related gastroduodenal diseases is still controversial. We summarized a total of 25 case-control articles with 38 studies in this meta-analysis and evaluated the relationship between babA2 and clinical outcomes. The presence of babA2 may contribute to increased risk of peptic ulcer disease (PUD), especially duodenal ulcer, in western countries. In Asians, babA2 genotype only showed a marginal association with PUD risk, which requires further investigation.
Publish Date	2013-07-13 17:01
Citation	Chen MY, He CY, Meng X, Yuan Y. Association of Helicobacter pylori babA2 with peptic ulcer disease and gastric cancer. World J Gastroenterol 2013; 19(26): 4242-4251
URL	http://www.wjgnet.com/1007-9327/full/v19/i26/4242.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i26.4242

Full Article (PDF)	WJG-19-4242.pdf
Manuscript File	1985-Review.doc
Answering Reviewers	1985-Answering reviewers.pdf
Copyright License Agreement	1985-Copyright assignment.PDF
Non-Native Speakers of English Editing Certificate	1985-Language certificate.pdf
Peer-review Report	1985-Peer review.pdf
Scientific Editor Work List	1985-Scientific editor work list.doc