| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Long-term lamivudine for chronic hepatitis B and cirrhosis: A real-life cohort study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ming-Hua Su, Ai-Lian Lu, Shi-Hua Li, Shao-Hua Zhong, Bao-Jian Wang, Xiao-Li Wu, Yan-Yan Mo, Peng Liang, Zhi-Hong Liu, Rong Xie, Li-Xia He, Wu-Dao Fu and Jian-Ning Jiang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Guangxi |
2014GXNSFDA118023 |
|
| Corresponding Author |
Jian-Ning Jiang, Professor, Department of Infectious Disease, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Qingxiu District, Nanning 530021, Guangxi Zhuang Autonomous Region, China. jjianning@163.com |
| Key Words |
Hepatitis B virus; Lamivudine; Management; Liver cirrhosis; Outcome; Therapy |
| Core Tip |
Drug resistance and disease relapse are inevitable during long-term lamivudine treatment in some patients. However, as long as standardized procedures in combination with comprehensive management are used, viral replication can be inhibited to a large extent. Thus, liver function in patients can be maintained at a stable status for a long time, and the incidence rates of liver cirrhosis and hepatocellular carcinoma, as well as hepatitis B virus-related deaths, may be reduced. |
| Publish Date |
2015-12-09 17:57 |
| Citation |
Su MH, Lu AL, Li SH, Zhong SH, Wang BJ, Wu XL, Mo YY, Liang P, Liu ZH, Xie R, He LX, Fu WD, Jiang JN. Long-term lamivudine for chronic hepatitis B and cirrhosis: A real-life cohort study. World J Gastroenterol 2015; 21(46): 13087-13094 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i46/13087.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i46.13087 |
