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11/27/2015 2:08:00 PM | Browse: 928 | Download: 1456
Publication Name World Journal of Gastroenterology
Manuscript ID 19891
Country China
Received
2015-05-25 08:51
Peer-Review Started
2015-05-25 09:17
To Make the First Decision
2015-06-25 17:50
Return for Revision
2015-07-05 15:31
Revised
2015-07-26 21:47
Second Decision
2015-10-10 18:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-10-13 18:11
Articles in Press
2015-10-13 18:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-10-22 13:46
Typeset the Manuscript
2015-11-03 20:36
Publish the Manuscript Online
2015-11-27 14:01
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Allergy
Manuscript Type Case Control Study
Article Title Studied microRNA gene expression in human hepatocellular carcinoma by microRNA microarray techniques
Manuscript Source Unsolicited Manuscript
All Author List Jian-Xiang Niu, Xing-Kai Meng and Jian-Jun Ren
Funding Agency and Grant Number
Funding Agency Grant Number
Inner Mongolia Medical College Millions of Science and Technology Project in 2011 NY2011bw004
2010 Inner Mongolia Health Bureau of Medical and Health Research Project 2010038
Scientific Research Projects of the Inner Mongolia Autonomous Region High School in 2013 NJZY13416
Corresponding Author Dr. Jian-Jun Ren, Department of General Surgery of the Affiliated Hospital of Inner Mongolia Medical University, No. 42 Zhaowuda Road, Saihan Region, Huhehaote 010010, Inner Mongolia Autonomous Region, China. renjianjunzml@163.com
Key Words Hepatocellular carcinoma; MicroRNA; Expression; Microarray technologies; Radar chart
Core Tip There was a better understanding of the molecular mechanisms of microRNA (miRNA) expression changes involved in hepatocellular carcinoma, associated patients with aggressive malignancy and poor prognosis. The 35 hepatitis B virus cases were divided into two groups, a hepatocirrhosis group with 20 cases and a liver cancer group with 15 cases. 12 healthy people were used as a control. There were significant changes in miRNA expression between the three groups. miRNA-183 was the most up-regulated, followed by miRNA-373. miRNA-129 and miRNA-188 were both strongly down-regulated and miRNA-378 was down-regulated a small amount. The liver cancer group had greater changes, which indicated that changes in miRNA expression levels were caused by hepatocirrhosis. The liver cancer disease course then further increased these changes.
Publish Date 2015-11-27 14:01
Citation Niu JX, Meng XK, Ren JJ. Studied microRNA gene expression in human hepatocellular carcinoma by microRNA microarray techniques. World J Gastroenterol 2015; 21(44): 12605-12611
URL http://www.wjgnet.com/1007-9327/full/v21/i44/12605.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i44.12605
Full Article (PDF) WJG-21-12605.pdf
Full Article (Word) WJG-21-12605.doc
Manuscript File 19891-Review.doc
Answering Reviewers 19891-Answering reviewers.pdf
Audio Core Tip 19891-Audio core tip.WAV
Biostatistics Review Certificate 19891-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 19891-Conflict-of-interest statement.pdf
Copyright License Agreement 19891-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 19891-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 19891-Language certificate.pdf
Peer-review Report 19891-Peer-review(s).pdf
Scientific Misconduct Check 19891-Scientific misconduct check.pdf
Scientific Editor Work List 19891-Scientific editor work list.pdf