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Articles Published Processes
11/27/2015 2:08:00 PM | Browse: 1036 | Download: 1809
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Received |
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2015-05-25 08:51 |
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Peer-Review Started |
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2015-05-25 09:17 |
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To Make the First Decision |
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2015-06-25 17:50 |
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Return for Revision |
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2015-07-05 15:31 |
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Revised |
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2015-07-26 21:47 |
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Second Decision |
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2015-10-10 18:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-10-13 18:11 |
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Articles in Press |
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2015-10-13 18:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-10-22 13:46 |
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Typeset the Manuscript |
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2015-11-03 20:36 |
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Publish the Manuscript Online |
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2015-11-27 14:01 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Allergy |
| Manuscript Type |
Case Control Study |
| Article Title |
Studied microRNA gene expression in human hepatocellular carcinoma by microRNA microarray techniques
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jian-Xiang Niu, Xing-Kai Meng and Jian-Jun Ren |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Inner Mongolia Medical College Millions of Science and Technology Project in 2011 |
NY2011bw004 |
| 2010 Inner Mongolia Health Bureau of Medical and Health Research Project |
2010038 |
| Scientific Research Projects of the Inner Mongolia Autonomous Region High School in 2013 |
NJZY13416 |
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| Corresponding Author |
Dr. Jian-Jun Ren, Department of General Surgery of the Affiliated Hospital of Inner Mongolia Medical University, No. 42 Zhaowuda Road, Saihan Region, Huhehaote 010010, Inner Mongolia Autonomous Region,
China. renjianjunzml@163.com
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| Key Words |
Hepatocellular carcinoma; MicroRNA; Expression; Microarray technologies; Radar chart |
| Core Tip |
There was a better understanding of the molecular mechanisms of microRNA (miRNA) expression changes involved in hepatocellular carcinoma, associated patients with aggressive malignancy and poor prognosis. The 35 hepatitis B virus cases were divided into two groups, a hepatocirrhosis group with 20 cases and a liver cancer group with 15 cases. 12 healthy people were used as a control. There were significant changes in miRNA expression between the three groups. miRNA-183 was the most up-regulated, followed by miRNA-373. miRNA-129 and miRNA-188 were both strongly down-regulated and miRNA-378 was down-regulated a small amount. The liver cancer group had greater changes, which indicated that changes in miRNA expression levels were caused by hepatocirrhosis. The liver cancer disease course then further increased these changes.
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| Publish Date |
2015-11-27 14:01 |
| Citation |
Niu JX, Meng XK, Ren JJ. Studied microRNA gene expression in human hepatocellular carcinoma by microRNA microarray techniques. World J Gastroenterol 2015; 21(44): 12605-12611 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i44/12605.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i44.12605 |
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