Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	19934
Country	Italy

Received	2015-05-26 09:17
Peer-Review Started	2015-05-28 08:23
To Make the First Decision	2015-07-27 18:42
Return for Revision	2015-07-29 17:34
Revised	2015-07-30 00:21
Second Decision	2015-09-18 12:08
Accepted by Journal Editor-in-Chief	2015-09-19 04:28
Accepted by Executive Editor-in-Chief	2015-09-28 18:04
Articles in Press	2015-09-28 18:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-27 15:16
Publish the Manuscript Online	2015-11-17 12:17

ISSN	2150-5330 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Eosinophilic esophagitis: From pathophysiology to treatment
Manuscript Source	Invited Manuscript
All Author List	Alessandra D’Alessandro, Dario Esposito, Marcella Pesce, Rosario Cuomo, Giovanni Domenico De Palma and Giovanni Sarnelli
Funding Agency and Grant Number
Corresponding Author	Giovanni Sarnelli, MD, PhD, Department of Clinical Medicine and Surgery, Gastroenterology Unit, Federico II University of Naples, Via Sergio Pansini, 5, 80131 Naples, Italy. sarnelli@unina.it
Key Words	Eosinophilic esophagitis; Eotaxin; Immune system; Proton pump inhibitors-responsive eosinophilia; Endoscopic dilation
Core Tip	Eosinophilic esophagitis (EoE) is a chronic immune disease, characterized by a dense eosinophilic infiltrate in the esophagus, leading to bolus impaction and reflux-like symptoms. The pathophysiology of this entity is still unclear, however the involvement of both genetic and immune factors have been suggested. In this review we summarize the evidence on EoE pathophysiology and illustrate the safety and efficacy of the most recent medical and endoscopic treatments.
Publish Date	2015-11-17 12:17
Citation	D’Alessandro A, Esposito D, Pesce M, Cuomo R, De Palma GD, Sarnelli G. Eosinophilic esophagitis: From pathophysiology to treatment. World J Gastrointest Pathophysiol 2015; 6(4): 150-158
URL	http://www.wjgnet.com/2150-5330/full/v6/i4/150.htm
DOI	http://dx.doi.org/10.4291/wjgp.v6.i4.150

Full Article (PDF)	WJGP-6-150.pdf
Full Article (Word)	WJGP-6-150.doc
Manuscript File	19934-Review.docx
Answering Reviewers	19934-Answering reviewers.pdf
Audio Core Tip	19934-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19934-Conflict-of-interest statement.pdf
Copyright License Agreement	19934-Copyright assignment.pdf
Peer-review Report	19934-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19934-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19934-Scientific misconduct check.pdf
Scientific Editor Work List	19934-Scientific editor work list.pdf