Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	19938
Country	Italy

Received	2015-05-26 09:08
Peer-Review Started	2015-05-28 14:02
To Make the First Decision	2015-06-18 15:13
Return for Revision	2015-06-25 15:22
Revised	2015-07-15 04:07
Second Decision	2015-08-27 12:05
Accepted by Journal Editor-in-Chief	2015-08-28 07:32
Accepted by Executive Editor-in-Chief	2015-09-08 15:05
Articles in Press	2015-09-08 15:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-24 18:54
Publish the Manuscript Online	2015-11-12 18:51

ISSN	2150-5349 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Typical and atypical symptoms of gastro esophageal reflux disease: Does Helicobacter pylori infection matter?
Manuscript Source	Invited Manuscript
All Author List	Laurino Grossi, Antonio Francesco Ciccaglione and Leonardo Marzio
Funding Agency and Grant Number
Corresponding Author	Laurino Grossi, MD, Associate Professor, c/o Digestive Sciences Unit, School of Gastroenterology, G. d’Annunzio University Chieti-Pescara, Ospedale Spirito Santo, Via Fonte Romana, 8, 65124 Pescara, Italy. lgrossi@unich.it
Key Words	Gastro-esophageal reflux disease; Symptoms; Helicobacter pylori; Eradication; C13 urea breath test; pH-metry
Core Tip	This study aimed to investigate whether the presence of Helicobacter pylori (H. pylori) infection could affect the symptom pattern of patients with Gastro-esophageal reflux disease (GERD). GERD patients with H. pylori were predominantly affected by atypical symptoms (chest pain, respiratory and ENT features) whilst patients without infection mainly referred typical GERD symptoms (heartburn, regurgitation). Therefore, it seems reasonable to assume that H. pylori infection may have a role in GERD pathogenesis or at least in the modulation of symptoms appearance.
Publish Date	2015-11-12 18:51
Citation	Grossi L, Ciccaglione AF, Marzio L. Typical and atypical symptoms of gastro esophageal reflux disease: Does Helicobacter pylori infection matter? World J Gastrointest Pharmacol Ther 2015; 6(4): 238-243
URL	http://www.wjgnet.com/2150-5349/full/v6/i4/238.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v6.i4.238

Full Article (PDF)	WJGPT-6-238.pdf
Full Article (Word)	WJGPT-6-238.doc
Manuscript File	19938-Review.doc
Answering Reviewers	19938-Answering reviewers.pdf
Audio Core Tip	19938-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19938-Conflict-of-interest statement.pdf
Copyright License Agreement	19938-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	19938-Institutional review board statement.pdf
Peer-review Report	19938-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19938-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19938-Scientific misconduct check.pdf
Scientific Editor Work List	19938-Scientific editor work list.pdf