Publication Name	World Journal of Gastroenterology
Manuscript ID	19943
Country	United States

Received	2015-05-26 08:57
Peer-Review Started	2015-05-27 14:37
To Make the First Decision	2015-06-23 15:03
Return for Revision	2015-06-26 17:43
Revised	2015-07-08 14:54
Second Decision	2015-09-28 16:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-09-30 10:29
Articles in Press	2015-09-30 10:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-21 11:28
Publish the Manuscript Online	2015-11-11 13:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Advances in alcoholic liver disease: An update on alcoholic hepatitis
Manuscript Source	Invited Manuscript
All Author List	Randy Liang, Andy Liu, Ryan B Perumpail, Robert J Wong and Aijaz Ahmed
Funding Agency and Grant Number
Corresponding Author	Aijaz Ahmed, MD, Associate Professor, Medical Director, Division of Gastroenterology and Hepatology, Stanford University School of Medicine, 750 Welch Road, Suite 210, Palo Alto, CA 94305, United States. aijazahmed@stanford.edu
Key Words	Alcoholic Hepatitis; Maddrey discriminant function; Corticosteroids; Pentoxifylline; Alcoholic liver disease
Core Tip	Alcoholic hepatitis is a pro-inflammatory chronic liver disease that is associated with high short-term morbidity and mortality in the setting of chronic alcohol use. Management consists of a multidisciplinary approach including alcohol cessation, fluid and electrolyte correction, treatment of alcohol withdrawal, and pharmacological therapy based on the severity of the disease. Pharmacological treatment for severe alcoholic hepatitis, as defined by Maddrey’s discriminant function ≥ 32, consists of either prednisolone or pentoxifylline for a period of four weeks. The body of evidence in favor of corticosteroids has been greater than pentoxifylline, although there are higher risks of complications.
Publish Date	2015-11-11 13:34
Citation	Liang R, Liu A, Perumpail RB, Wong RJ, Ahmed A. Advances in alcoholic liver disease: An update on alcoholic hepatitis. World J Gastroenterol 2015; 21(42): 11893-11903
URL	http://www.wjgnet.com/1007-9327/full/v21/i42/11893.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i42.11893

Full Article (PDF)	WJG-21-11893.pdf
Full Article (Word)	WJG-21-11893.doc
Manuscript File	19943-Review.docx
Answering Reviewers	19943-Answering reviewers.pdf
Audio Core Tip	19943-Audio core tip.wma
Copyright License Agreement	19943-Copyright Assignment.pdf
Peer-review Report	19943-Peer-review(s).pdf
Scientific Misconduct Check	19943-Scientific misconduct check.pdf
Scientific Editor Work List	19943-Scientific editor work list.pdf