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Articles Published Processes
9/15/2014 8:54:00 PM | Browse: 1097 | Download: 1361
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Received |
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2013-01-20 11:23 |
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Peer-Review Started |
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2013-01-21 11:45 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2013-03-06 18:15 |
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Revised |
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Publication Fee Transferred |
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Second Decision by Editor |
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2013-04-28 14:30 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2013-04-29 01:12 |
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Articles in Press |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-07-05 16:25 |
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Publish the Manuscript Online |
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2013-07-13 17:01 |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Epithelial toll-like receptor 9 signaling in colorectal inflammation and cancer: Clinico-pathogenic aspects
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| Manuscript Source |
Invited Manuscript |
| All Author List |
István Fűri, Ferenc Sipos, Tiana M Germann, Alexandra Kalmár, Zsolt Tulassay, Béla Molnár and Györgyi Műzes |
| Funding Agency and Grant Number |
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| Corresponding Author |
Ferenc Sipos MD, PhD, 2nd Department of Internal Medicine, Semmelweis University, Szentkirályi str. 46., 1088 Budapest, Hungary. dr.siposf@gmail.com |
| Key Words |
Toll-like receptor 9; Synthetic oligodeoxynucleotide sequences; DNA-based immunomodulatory sequences; Colorectal cancer; Inflammatory bowel diseases |
| Core Tip |
Toll-like receptor 9 mediated signaling influences and regulates the severity of mucosal inflammation, and seems to have a protective role against malignant transformation. The modulation of toll-like receptor 9 signaling by synthetic oligodeoxynucleotide agonists or antagonists seems to have beneficial therapeutic effect in inflammatory and cancerous colonic disorders. |
| Publish Date |
2013-07-13 17:01 |
| Citation |
Fűri I, Sipos F, Germann TM, Kalmár A, Tulassay Z, Molnár B, Műzes G. Epithelial toll-like receptor 9 signaling in colorectal inflammation and cancer: Clinico-pathogenic aspects. World J Gastroenterol 2013; 19(26): 4119-4126
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| URL |
http://www.wjgnet.com/1007-9327/full/v19/i26/4119.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v19.i26.4119 |
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