Publication Name	World Journal of Biological Chemistry
Manuscript ID	19999
Country	United States

Received	2015-05-27 11:07
Peer-Review Started	2015-05-29 13:43
To Make the First Decision	2015-06-18 15:11
Return for Revision	2015-06-25 16:42
Revised	2015-07-07 11:07
Second Decision	2015-08-27 12:08
Accepted by Journal Editor-in-Chief	2015-08-28 11:16
Accepted by Executive Editor-in-Chief	2015-09-30 18:36
Articles in Press	2015-09-30 18:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-11-03 07:25
Publish the Manuscript Online	2015-11-23 10:19

ISSN	1949-8454 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Review
Article Title	Targeting amino acid metabolism in cancer growth and anti-tumor immune response
Manuscript Source	Invited Manuscript
All Author List	Elitsa Ananieva
Funding Agency and Grant Number
Corresponding Author	Elitsa Ananieva, PhD, Assistant Professor of Biochemistry, Biochemistry and Nutrition, Des Moines University, 3200 Grand Avenue, Des Moines, IA 50312, United States. elitsa.ananieva-stoyanova@dmu.edu
Key Words	Amino acid metabolism; T cells; Anti-tumor immune response; Tumor microenvironment; Cancer therapy
Core Tip	Amino acid metabolism has been a focus of increased attention by cancer researchers and immu?nologists due to its importance for the metabolic reprogramming of proliferating cells. Many amino acid enzymes are described as immunosuppressive in the tumor microenvironment and targeted for cancer therapy. This review addresses the metabolic control of tumor progression in the context of anti-tumor immunity and discusses current and future therapeutic approaches. Special emphasis is given to the emerging role of branched chain amino acid metabolism in cancer and immunity highlighting some recent work by our research group.
Publish Date	2015-11-23 10:19
Citation	Ananieva E. Targeting amino acid metabolism in cancer growth and anti-tumor immune response. World J Biol Chem 2015; 6(4): 281-289
URL	http://www.wjgnet.com/1949-8454/full/v6/i4/281.htm
DOI	http://dx.doi.org/10.4331/wjbc.v6.i4.281

Full Article (PDF)	WJBC-6-281.pdf
Full Article (Word)	WJBC-6-281.doc
Manuscript File	19999-Review.docx
Answering Reviewers	19999-Answering reviewers.pdf
Audio Core Tip	19999-Audio core tip.MP3
Conflict-of-Interest Disclosure Form	19999-Conflict-of-interest statement.pdf
Copyright License Agreement	19999-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	19999-Language certificate.pdf
Peer-review Report	19999-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19999-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19999-Scientific misconduct check.pdf
Scientific Editor Work List	19999-Scientific editor work list.pdf