Publication Name	World Journal of Hepatology
Manuscript ID	20030
Country	United States

Received	2015-05-28 10:12
Peer-Review Started	2015-05-30 15:34
To Make the First Decision	2015-06-18 15:11
Return for Revision	2015-06-25 16:52
Revised	2015-07-10 03:34
Second Decision	2015-10-08 13:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-10-19 15:08
Articles in Press	2015-10-19 15:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-22 14:21
Publish the Manuscript Online	2015-11-09 18:35

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Pathology
Manuscript Type	Editorial
Article Title	Clinical and biological significance of precursor lesions of intrahepatic cholangiocarcinoma
Manuscript Source	Invited Manuscript
All Author List	Mark Ettel, Ogechukwu Eze and Ruliang Xu
Funding Agency and Grant Number
Corresponding Author	Ruliang Xu, MD, PhD, Department of Pathology, NYU School of Medicine, 560 First Avenue, New York, NY 10016, United States. ruliang.xu@nyumc.org
Key Words	Intraepithelial neoplasia; Von Meyenburg complex or bile duct hamartoma; Bile duct adenoma; Intrahepatic cholangiocarcinoma; Intraductal papillary neoplasm of the bile duct
Core Tip	This manuscript highlights the important development in the research field of intrahepatic cholangiocarcinogenesis, and summarizes some key points related to progression from the precursor lesions to the intrahepatic cholangiocarcinoma, including their molecular genetics. Each individual precursor or potential precursor is linked to the cancer by the clinical, histological and molecular association.
Publish Date	2015-11-09 18:35
Citation	Ettel M, Eze O, Xu R. Clinical and biological significance of precursor lesions of intrahepatic cholangiocarcinoma. World J Hepatol 2015; 7(25): 2563-2570
URL	http://www.wjgnet.com/1948-5182/full/v7/i25/2563.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i25.2563

Full Article (PDF)	WJH-7-2563.pdf
Full Article (Word)	WJH-7-2563.doc
Manuscript File	20030-Review.docx
Answering Reviewers	20030-Answering reviewers.pdf
Audio Core Tip	20030-Audio core tip.wav
Conflict-of-Interest Disclosure Form	20030-Conflict-of-interest statement.pdf
Copyright License Agreement	20030-Copyright assignment.pdf
Peer-review Report	20030-Peer-review(s).pdf
Scientific Misconduct Check	20030-Scientific misconduct check.pdf
Scientific Editor Work List	20030-Scientific editor work list.pdf