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Articles Published Processes
12/31/2015 1:27:00 PM | Browse: 1011 | Download: 1465
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Received |
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2015-05-28 10:02 |
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Peer-Review Started |
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2015-05-29 12:00 |
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To Make the First Decision |
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2015-08-31 08:54 |
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Return for Revision |
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2015-08-31 16:08 |
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Revised |
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2015-09-14 00:00 |
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Second Decision |
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2015-09-23 19:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-09-30 08:46 |
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Articles in Press |
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2015-09-30 08:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-10-26 22:57 |
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Typeset the Manuscript |
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2015-12-10 20:15 |
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Publish the Manuscript Online |
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2015-12-31 13:27 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Topic Highlights |
| Article Title |
Targeting adeno-associated virus and adenoviral gene therapy for hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yi-Gang Wang, Pan-Pan Huang, Rong Zhang, Bu-Yun Ma, Xiu-Mei Zhou and Yan-Fang Sun |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81272687 |
| Zhejiang Provincial Public Welfare Technology Application Research Projects |
2014C33275 |
| Zhejiang Provincial Natural Science Foundation of China |
LZ13H160004 |
| the Grant for 521 Talent Project of Zhejiang Sci-Tech University |
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| Corresponding Author |
Dr. Yi-Gang Wang, Xinyuan Institute of Medicine and Biotechnology, School of Life Sciences, Zhejiang Sci-Tech University, No. 5, Road 2, Xiasha District, Hangzhou 310018, Zhejiang Province, China. wangyigang43@163.com
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| Key Words |
Hepatocellular carcinoma; Adeno-associated virus; Adenovirus; Virus vectors |
| Core Tip |
This review summarizes the basic knowledge, current advances, and future challenges and prospects of adeno-associated virus (AAV) and adenoviruses as vectors for gene therapy of hepatocellular carcinoma. This paper also reviews the clinical trials of gene therapy using adenovirus vectors, immunotherapy, toxicity and immunological barriers for AAV and adenoviruses, and proposes several alternative strategies to overcome the therapeutic barriers to using AAV and adenoviruses as vectors.
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| Publish Date |
2015-12-31 13:27 |
| Citation |
Wang YG, Huang PP, Zhang R, Ma BY, Zhou XM, Sun YF. Targeting adeno-associated virus and adenoviral gene therapy for hepatocellular carcinoma. World J Gastroenterol 2016; 22(1): 326-337 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i1/326.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i1.326 |
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