Publication Name	World Journal of Cardiology
Manuscript ID	20065
Country	United States

Received	2015-05-28 08:52
Peer-Review Started	2015-06-01 09:41
To Make the First Decision	2015-07-03 16:45
Return for Revision	2015-07-10 19:27
Revised	2015-08-21 01:52
Second Decision	2015-09-10 08:20
Accepted by Journal Editor-in-Chief	2015-09-12 00:12
Accepted by Executive Editor-in-Chief	2015-09-18 14:12
Articles in Press	2015-09-18 14:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-11-11 17:42
Publish the Manuscript Online	2015-11-30 08:10

ISSN	1949-8462 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Systematic Reviews
Article Title	Digoxin: A systematic review in atrial fibrillation, congestive heart failure and post myocardial infarction
Manuscript Source	Invited Manuscript
All Author List	Sebastiano Virgadamo, Richard Charnigo, Yousef Darrat, Gustavo Morales and Claude S Elayi
Funding Agency and Grant Number
Corresponding Author	Claude S Elayi, MD, Department of Cardiology, University of Kentucky Gill Heart Institute and Veterans Affairs Medical Center, 326 C.T. Wethington Bldg. 900 South Limestone Street, Lexington, KY 40536, United States. samy-claude.elayi@uky.edu
Key Words	Mortality; Myocardial infarction; Heart failure; Atrial fibrillation; Digoxin
Core Tip	This systematic review evaluates mortality with the use of digoxin in congestive heart failure (CHF) with sinus rhythm, atrial fibrillation with and without CHF, and post myocardial infarction. In patients with CHF with sinus rhythm, there continues to be a niche for digoxin use as an adjunctive therapy for symptomatic control with the understanding that there is no effect on mortality. The role for digoxin among patients who only have atrial fibrillation seems very limited; however, those with atrial fibrillation and systolic congestive heart failure or post myocardial infarction need further assessment as many questions remain regarding the benefit of digoxin in this population.
Publish Date	2015-11-30 08:10
Citation	Virgadamo S, Charnigo R, Darrat Y, Morales G, Elayi CS. Digoxin: A systematic review in atrial fibrillation, congestive heart failure and post myocardial infarction. World J Cardiol 2015; 7(11): 808-816
URL	http://www.wjgnet.com/1949-8462/full/v7/i11/808.htm
DOI	http://dx.doi.org/10.4330/wjc.v7.i11.808

Full Article (PDF)	WJC-7-808.pdf
Full Article (Word)	WJC-7-808.doc
Manuscript File	20065-Review.docx
Answering Reviewers	20065-Answering reviewers.pdf
Audio Core Tip	20065-Audio core tip.mp3
Biostatistics Review Certificate	20065-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	20065-Conflict-of-interest statement.pdf
Copyright License Agreement	20065-Copyright assignment.pdf
Peer-review Report	20065-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	20065-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	20065-Scientific misconduct check.pdf
Scientific Editor Work List	20065-Scientific editor work list.pdf