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Articles Published Processes
9/16/2014 9:55:00 AM | Browse: 706 | Download: 964
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Received |
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2013-01-20 19:13 |
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Peer-Review Started |
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2013-01-21 15:55 |
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To Make the First Decision |
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2013-02-21 18:30 |
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Return for Revision |
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2013-02-25 16:12 |
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Revised |
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2013-03-25 20:08 |
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Second Decision |
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2013-04-09 20:21 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-04-10 07:51 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-05-16 18:34 |
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Publish the Manuscript Online |
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2013-05-20 14:33 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Autobiography |
Article Title |
Overexpression of p42.3 promotes cell growth and tumorigenicity in hepatocellular carcinoma
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Manuscript Source |
Invited Manuscript |
All Author List |
Wei Sun, Wei-Wei Dong, Lin-Lin Mao, Wen-Mei Li, Jian-Tao Cui, Rui Xing and You-Yong Lu |
Funding Agency and Grant Number |
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Corresponding Author |
Rui Xing, PhD, Laboratory of Molecular Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital/Institute, No. 52 Fucheng Road, Haidian District, Beijing 100142, China. sherry19820420@hotmail.com
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Key Words |
p42.3; Hepatocellular carcinoma; HepG2; Overexpression; Tumorigenicity |
Core Tip |
p42.3 is a novel tumor-specific and mitosis phase-dependent expression gene. It is believed to be involved in tumorigenesis in gastric and colorectal cancer. To the best of our knowledge, this is the first study to investigate the expression and function of p42.3 in hepatocellular carcinoma (HCC). We found that p42.3 promotes tumorigenicity and tumor growth in HepG2 cells and is overexpressed in HCC. These results suggest that p42.3 may act as a novel tumor biomarker and aid in the development of improved therapeutic strategies.
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Publish Date |
2013-05-20 14:33 |
Citation |
Adas G, Adas M, Arikan S, Sarvan AK, Toklu AS, Mert S, Barut G, Kamali S, Koc B, Tutal F. Effect of growth hormone, hyperbaric oxygen and combined therapy on the gastric serosa. World J Gastroenterol 2013; 19(19): 2904-2912 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i19/2904.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i19.2904 |
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