Publication Name	World Journal of Clinical Oncology
Manuscript ID	20105
Country	United States

Received	2015-05-28 16:49
Peer-Review Started	2015-05-31 12:33
To Make the First Decision	2015-07-28 10:42
Return for Revision	2015-08-07 18:18
Revised	2015-08-12 05:11
Second Decision	2015-08-25 17:34
Accepted by Journal Editor-in-Chief	2015-08-26 00:45
Accepted by Executive Editor-in-Chief	2015-08-31 16:54
Articles in Press	2015-08-31 16:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-11-29 18:21
Publish the Manuscript Online	2015-12-09 18:37

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Editorial
Article Title	Current role of spacers for prostate cancer radiotherapy
Manuscript Source	Invited Manuscript
All Author List	Michael Pinkawa
Funding Agency and Grant Number
Corresponding Author	Michael Pinkawa, MD, Professor, Department of Radiation Oncology, RWTH Aachen University, Pauwelsstrasse 30, 52057 Aachen, Germany. mpinkawa@ukaachen.de
Key Words	External-beam radiotherapy; Intensity-modulated radiotherapy; Brachytherapy; Spacer; Hydrogel; Biodegradable balloon; Hyaluronic acid; Collagen; Prostate cancer; Toxicity
Core Tip	Radiotherapy is widely used for the treatment of prostate cancer. Technical advances allow improved tumor control with increasing prescription doses, but rectal wall is known to be a dose-limiting organ. A new method that has been increasingly used in the last years is the application of a biodegradable spacer to increase the distance between the prostate and rectal wall. Clinical studies, including a prospective randomized trial, have reported considerable dosimetric advantages for the rectum, well tolerated insertion procedures and radiotherapy treatments.
Publish Date	2015-12-09 18:37
Citation	Pinkawa M. Current role of spacers for prostate cancer radio­therapy. World J Clin Oncol 2015; 6(6): 189-193
URL	http://www.wjgnet.com/2218-4333/full/v6/i6/189.htm
DOI	http://dx.doi.org/10.5306/wjco.v6.i6.189

Full Article (PDF)	WJCO-6-189.pdf
Full Article (Word)	WJCO-6-189.doc
Manuscript File	20105-Review.doc
Answering Reviewers	20105-Answering reviewers.pdf
Audio Core Tip	20105-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20105-Conflict-of-interest statement.pdf
Copyright License Agreement	20105-Copyright assignment.pdf
Peer-review Report	20105-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	20105-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	20105-Scientific misconduct check.pdf
Scientific Editor Work List	20105-Scientific editor work list.pdf