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11/17/2015 12:17:00 PM | Browse: 11920 | Download: 714
Publication Name World Journal of Gastrointestinal Pathophysiology
Manuscript ID 20112
Country/Territory Italy
Received
2015-05-28 17:04
Peer-Review Started
2015-05-28 21:47
To Make the First Decision
2015-07-02 13:33
Return for Revision
2015-07-10 15:02
Revised
2015-07-21 00:00
Second Decision
2015-10-08 12:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-10-19 15:25
Articles in Press
2015-10-19 15:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-10-23 16:32
Publish the Manuscript Online
2015-11-17 12:17
ISSN 2150-5330 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Editorial
Article Title Starring role of toll-like receptor-4 activation in the gut-liver axis
Manuscript Source Invited Manuscript
All Author List Simone Carotti, Michele Pier Luca Guarino, Umberto Vespasiani-Gentilucci and Sergio Morini
Funding Agency and Grant Number
Corresponding author Sergio Morini, MD, Laboratory of Microscopic and Ultrastructural Anatomy, School of Medicine, University Campus Bio-Medico of Rome, Via Alvaro Del Portillo, 21, 00128 Rome, Italy. s.morini@unicampus.it
Keywords Gut microbiota; Dysbiosis; Toll-like receptor 4; Gut motility; Lipopolysaccharide tolerance; Non-alcoholic fatty liver disease; Chronic hepatitis; Intestinal barrier function; Liver fibrosis
Core Tip Liver disease is associated with significant changes in intestinal microbiota, but whether liver disease modifies the complement of gut bacteria or dysbiosis causes liver disease is not clearly understood. This review outlines current knowledge on the gut-liver axis, with a particular focus on the role of toll-like receptor 4 activation in functional gastrointestinal disorders, liver inflammation and fibrosis.
Publish Date 2015-11-17 12:17
Citation Carotti S, Guarino MPL, Vespasiani-Gentilucci U, Morini S. Starring role of toll-like receptor-4 activation in the gut-liver axis. World J Gastrointest Pathophysiol 2015; 6(4): 99-109
Url http://www.wjgnet.com/2150-5330/full/v6/i4/99.htm
DOI http://dx.doi.org/10.4291/wjgp.v6.i4.99
Full Article (PDF) WJGP-6-99.pdf
Full Article (Word) WJGP-6-99.doc
Manuscript File 20112-Review.docx
Answering Reviewers 20112-Answering reviewers.pdf
Audio Core Tip 20112-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 20112-Conflict-of-interest statement.pdf
Copyright License Agreement 20112-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 20112-Language certificate.pdf
Peer-review Report 20112-Peer-review(s).pdf
Scientific Misconduct Check 20112-Scientific misconduct check.pdf
Scientific Editor Work List 20112-Scientific editor work list.pdf