Publication Name	World Journal of Clinical Oncology
Manuscript ID	20142
Country	China

Received	2015-05-29 09:58
Peer-Review Started	2015-05-30 20:42
First Decision by Editorial Office Director
Return for Revision	2015-08-23 19:08
Revised	2015-10-16 22:09
Publication Fee Transferred
Second Decision by Editor	2015-12-03 17:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2015-12-11 16:02
Articles in Press	2015-12-11 16:02
Edit the Manuscript by Language Editor	2015-12-14 14:44
Typeset the Manuscript	2016-01-18 09:44
Publish the Manuscript Online	2016-01-30 17:42

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Minireviews
Article Title	Targeting metabolism in breast cancer: How far we can go?
Manuscript Source	Invited Manuscript
All Author List	Jing-Pei Long, Xiao-Na Li and Feng Zhang
Funding Agency and Grant Number
Corresponding Author	Feng Zhang, MD, PhD, Department of Surgery, Hangzhou Women’s Hospital, Kunpeng Road 369, Hangzhou 310008, Zhejiang Province, China. zhang3772@qq.com
Key Words	Breast cancer; Targeted therapy; Metabolism; Drug resistance; Chemotherapy
Core Tip	Breast cancer cells display distinct metabolic characteristics according to different molecular phenotypes. There may be crosstalk with the estrogen receptor and human epidermal growth factor receptor-2 signal pathways in the metabolic regulation in breast cancer cells that make it more complex to evaluate the efficiency of an anti-metabolic drug. On the other hand, the research on target metabolism in breast cancer will also largely help us to understand the complicated mechanism by which an anti-metabolic drug improves the efficacy of cancer therapy or overcomes drug resistance.
Publish Date	2016-01-30 17:42
Citation	Long JP, Li XN, Zhang F. Targeting metabolism in breast cancer: How far we can go? World J Clin Oncol 2016; 7(1): 122-130
URL	http://www.wjgnet.com/2218-4333/full/v7/i1/122.htm
DOI	http://dx.doi.org/10.5306/wjco.v7.i1.122

Full Article (PDF)	WJCO-7-122.pdf
Full Article (Word)	WJCO-7-122.doc
Manuscript File	20142-Review.docx
Answering Reviewers	20142-Answering reviewers.pdf
Audio Core Tip	20142-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20142-Conflict-of-interest statement.pdf
Copyright License Agreement	20142-Copyright assignment.pdf
Peer-review Report	20142-Peer-review(s).pdf
Scientific Misconduct Check	20142-Scientific misconduct check.pdf
Scientific Editor Work List	20142-Scientific editor work list.pdf