Publication Name	World Journal of Clinical Oncology
Manuscript ID	20178
Country	United States

Received	2015-05-29 17:19
Peer-Review Started	2015-05-31 17:16
To Make the First Decision	2015-07-27 15:49
Return for Revision	2015-08-04 11:29
Revised	2015-09-04 05:58
Second Decision	2015-11-09 10:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-11-25 15:47
Articles in Press	2015-11-25 15:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-18 10:11
Publish the Manuscript Online	2016-01-30 17:42

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Minireviews
Article Title	Role of copper transporters in platinum resistance
Manuscript Source	Invited Manuscript
All Author List	Deepak Kilari, Elizabeth Guancial and Eric S Kim
Funding Agency and Grant Number
Corresponding Author	Eric S Kim, MD, Department of Medicine, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY 14642, United States. eric_kim@urmc.rochester.edu
Key Words	Resistance; Cisplatin; Copper transporter receptor 1; Copper transporter; Copper transporter receptor 2; ATP7A; ATP7B
Core Tip	Platinum (Pt)-based chemotherapy is the backbone of treatment for various solid malignancies in both curative and palliative settings. However, the efficacy of Pt is limited by toxicity and inevitable resistance. Hence, it is important to understand the mechanisms of Pt resistance to not only identify treatment non-responders, but more importantly to help develop strategies to overcome resistance and improve efficacy. We herein discuss our current understanding of the mechanisms of Pt resistance, with a particular emphasis on the role of copper transporter receptor 1 in Pt resistance.
Publish Date	2016-01-30 17:42
Citation	Kilari D, Guancial E, Kim ES. Role of copper transporters in platinum resistance. World J Clin Oncol 2016; 7(1): 106-113
URL	http://www.wjgnet.com/2218-4333/full/v7/i1/106.htm
DOI	http://dx.doi.org/10.5306/wjco.v7.i1.106

Full Article (PDF)	WJCO-7-106.pdf
Full Article (Word)	WJCO-7-106.doc
Manuscript File	20178-Review.docx
Answering Reviewers	20178-Answering reviewers.pdf
Audio Core Tip	20178-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20178-Conflict-of-interest statement.pdf
Copyright License Agreement	20178-Copyright assignment.pdf
Peer-review Report	20178-Peer-review(s).pdf
Scientific Misconduct Check	20178-Scientific misconduct check.pdf
Scientific Editor Work List	20178-Scientific editor work list.pdf