Publication Name	World Journal of Gastroenterology
Manuscript ID	20193
Country	Italy

Received	2015-05-29 20:30
Peer-Review Started	2015-06-03 16:37
To Make the First Decision	2015-09-11 08:58
Return for Revision	2015-09-15 15:41
Revised	2015-10-06 21:55
Second Decision	2015-11-03 09:17
Accepted by Journal Editor-in-Chief	2015-11-03 14:12
Accepted by Company Editor-in-Chief	2015-11-13 16:02
Articles in Press	2015-11-13 16:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-16 17:08
Publish the Manuscript Online	2016-01-06 16:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Adjuvant chemotherapy for resected colorectal cancer metastases: Literature review and meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Giovanni Brandi, Stefania De Lorenzo, Margherita Nannini, Stefania Curti, Marta Ottone, Filippo Gustavo Dall’Olio, Maria Aurelia Barbera, Maria Abbondanza Pantaleo and Guido Biasco
Funding Agency and Grant Number
Corresponding Author	Giovanni Brandi, MD, PhD, Department of Experimental, Diagnostic and Specialty Medicine, Sant’Orsola-Malpighi Hospital and “G. Prodi” Interdepartmental Center for Cancer Research, Bologna University, via Massarenti 9, 40138 Bologna, Italy. giovanni.brandi@unibo.it
Key Words	Liver metastases; Adjuvant chemotherapy; Metastasectomy; Colorectal cancer; Adjuvant hepatic artery infusion
Core Tip	Surgical resection is the only option of cure for patients with metastatic colorectal cancer (CRC). The risk of recurrence within 18 mo after metastasectomy is about 75% and the liver is the main organ involved. However, there is still no standard treatment and the effective role of adjuvant therapy remains controversial. The aim of this review is to summarize current knowledge on the role of systemic chemotherapy and regional chemotherapy with hepatic arterial infusion in the management of patients after resection of metastases from CRC.
Publish Date	2016-01-06 16:13
Citation	Brandi G, De Lorenzo S, Nannini M, Curti S, Ottone M, Dall’Olio FG, Barbera MA, Pantaleo MA, Biasco G. Adjuvant chemotherapy for resected colorectal cancer metastases: Literature review and meta-analysis. World J Gastroenterol 2016; 22(2): 519-533
URL	http://www.wjgnet.com/1007-9327/full/v22/i2/519.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i2.519

Full Article (PDF)	WJG-22-519.pdf
Full Article (Word)	WJG-22-519.doc
Manuscript File	20193-Review.doc
Answering Reviewers	20193-Answering reviewers.pdf
Audio Core Tip	20193-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20193-Conflict-of-interest statement.pdf
Copyright License Agreement	20193-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	20193-Language certificate.pdf
Peer-review Report	20193-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	20193-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	20193-Scientific misconduct check.pdf
Scientific Editor Work List	20193-Scientific editor work list.pdf